The theory of memory binding and its usefulness in early diagnosis of Alzheimer's disease

The thesis focuses on memory binding from the perspective of cognitive psychology, neuropsychology and presents structural correlates of memory. It reflects current research and concepts such as Subjective Cognitive Disorder (SCD) and mild cognitive impairment (MCI) and advocates previously created units for the continuum of Alzheimer's disease. The aim of the work is to verify the functionality of the Czech version of the Buschke Memory binding test for clinical practice. In the Empirical section it focuses on the MBT memory binding capability test and performance comparison in three groups of the sample population (without cognitive deficit, SCD and MCI). Statistical testing (ANCOVA) found a significant difference in performance in selected scores between the three groups. The results showed that memory binding performance is impaired as the deficit depth progresses. In our sample, no significant performance difference could be found between the cognitively normal group and the SCD group. The references are cited accoding to APA 7th edition manual. Key words Alzheimer's disease, neuropsychology, cognition, memory bindin