Advances in the diagnosis and treatment of Parkinson's disease

Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Biological and Medical Sciences Author: Hana Koťátková Supervisor: PharmDr. Iveta Nejmanova, Ph.D. Form: Bachelor thesis Field of study: Medical Bioanalytics Title: Advances in the diagnosis and treatment of Parkinson's diseases The aim of the work: The aim is to clearly write current and developed diagnostic and treatment procedures for Parkinson's disease. The retrieved and collected information is analyzed and summarized. Main goals: The topic of this bachelor thesis is Parkinson's disease, especially its diagnosis and therapy. The introductory chapters deal with Parkinsonism, the epidemiology and etiopathogenesis of Parkinson's diseases, as well as the clinical symptoms. Diagnosis and therapy occupy the largest part of this bachelor thesis. Clinical diagnostics no longer focuses only on motor symptoms, but also includes non-motor ones. Various diagnostic criteria, scales and tests that are currently used will be mentioned. This bachelor thesis also includes a chapter on biomarkers of Parkinson's disease, because there is great potential. The chapters about therapy mention current pharmacotherapies, their development, neurosurgical treatment and the effects of immunotherapy and gene therapy. Conclusion: From the..