Tato bakalářská práce se zabývá genetikou onemocnění koronárních tepen. Díky studiu rizikových genetických variací je možné identifikovat ohrožené pacienty a vyvíjet cílenou léčbu. V první kapitole se zmiňuje anatomie, histologie a patofyziologie koronárních tepen. Druhá kapitola je zaměřena na dosavadní znalosti dědičnosti onemocnění koronárních tepen. Ve třetí kapitole jsou zmíněny dva genomické projekty, které přispěly ke studiu variací u onemocnění koronárních tepen, a způsoby čtení dat z jejich databází. Těmito projekty jsou 1000 Genomes Project a CARDIoGRAM plus CD4 consortium. Na základě dat z 1000 Genomes databáze byl získán referenční panel vazebné nerovnováhy. Dále byla provedena asociační analýza na základě dat ze souhrnné statis...
Coronary artery disease is the leading global cause of mortality. Long recognized to be heritable, r...
Cardiovascular diseases are affected by multiple factors like genetic as well as environmental hence...
Contains fulltext : 98050.pdf (publisher's version ) (Open Access)Coronary artery ...
This dissertation should supplement the knowledge of the genetic coronary heart disease (CHD) archit...
Ateroskleroza je kompleksna, hronična i progresivna bolest arterijskih krvnih sudova koja se razvija...
Cardiovascular diseases (CVD) belong to the most current issues nowadays and they are the most frequ...
Coronary artery disease is a major socioeconomic problem in industrialized as well as in developing ...
The main expansion of the discovery of genetic variants associated with complex diseases has occurre...
Tato bakalářská práce se zabývá genetikou onemocnění koronárních tepen. Díky studiu rizikových genet...
Coronary artery disease is multifactorial. In recent times due to the development of modern molecula...
OBJECTIVE: Only a small fraction of coronary artery disease (CAD) heritability has been explained by...
One of the greatest challenges facing biomedical research since the sequencing of the human genome h...
Znanstveni napredak u području genetike otvorio je nove mogućnosti u dijagnostici nasljednih kardio...
This thesis, titled __Genetic and pharmacogenetic determinants of cardiovascular disease__ is divide...
Coronary artery disease (CAD) is a complex disease with environmental and genetic determinants. Many...
Coronary artery disease is the leading global cause of mortality. Long recognized to be heritable, r...
Cardiovascular diseases are affected by multiple factors like genetic as well as environmental hence...
Contains fulltext : 98050.pdf (publisher's version ) (Open Access)Coronary artery ...
This dissertation should supplement the knowledge of the genetic coronary heart disease (CHD) archit...
Ateroskleroza je kompleksna, hronična i progresivna bolest arterijskih krvnih sudova koja se razvija...
Cardiovascular diseases (CVD) belong to the most current issues nowadays and they are the most frequ...
Coronary artery disease is a major socioeconomic problem in industrialized as well as in developing ...
The main expansion of the discovery of genetic variants associated with complex diseases has occurre...
Tato bakalářská práce se zabývá genetikou onemocnění koronárních tepen. Díky studiu rizikových genet...
Coronary artery disease is multifactorial. In recent times due to the development of modern molecula...
OBJECTIVE: Only a small fraction of coronary artery disease (CAD) heritability has been explained by...
One of the greatest challenges facing biomedical research since the sequencing of the human genome h...
Znanstveni napredak u području genetike otvorio je nove mogućnosti u dijagnostici nasljednih kardio...
This thesis, titled __Genetic and pharmacogenetic determinants of cardiovascular disease__ is divide...
Coronary artery disease (CAD) is a complex disease with environmental and genetic determinants. Many...
Coronary artery disease is the leading global cause of mortality. Long recognized to be heritable, r...
Cardiovascular diseases are affected by multiple factors like genetic as well as environmental hence...
Contains fulltext : 98050.pdf (publisher's version ) (Open Access)Coronary artery ...