peer reviewedType 2 diabetes (T2D) is a complex disease characterized by different pathophysiological mechanisms. None of the available antidiabetic agents is able to target all the underlying abnormalities so that combined therapies are often mandatory. Despite that, numerous patients remain with a poorly controlled T2D, which exposes them to an increased risk of vascular complications. New glucose-lowering compounds are currently in development by the pharmaceutical industry in preclinical or already clinical phases. Some belong to well-known pharmacological classes and should be commercialized in a rather near future. Other combine different approaches that are potentially complementary, either as fixed-dose combinations or with original...
peer reviewedADOPT ("A Diabetes Outcome Progression Trial") is a double-blind, controlled clinical t...
Sodium-glucose cotransporter 2 (SGLT2) inhibitors are a class of drugs which offer cardiovascular (C...
peer reviewedBeyond lifestyle changes, the management of type 2 diabetes comprises the administratio...
peer reviewedType 2 diabetes (T2D) is a complex disease with multiple defects, which generally requi...
peer reviewedThe diabetic patient, when type 2 diabetes is newly diagnosed, raises a therapeutic pro...
peer reviewedType 2 diabetes is a complex disease characterized by a dual defect of insulin secretio...
peer reviewedType 2 diabetes is a complex disease combining several disturbances in various organs, ...
peer reviewedExenatide (Byetta) is a synthetic derivative of exendin-4 and an agonist of receptors o...
peer reviewedGlucagon-like peptide-1 (GLP-1) is a gut hormone secreted in response to the ingestion ...
peer reviewedKidney plays a role in glucose homeostasis, not only by its capacity to produce glucose...
peer reviewedIn a patient with type 2 diabetes not well controlled with a basal insulin - metformin ...
Insulin therapy, often initiated after hygiene and dietary measures and non-insulin antidiabetics, i...
peer reviewedManagement of type 1 diabetes essentially relies upon intensive insulin therapy adjuste...
peer reviewedType 1 diabetes (T1D) management is still complex. Some drugs have been proposed as adj...
peer reviewedGlucovance, recently launched by Merck-Lipha (Glucovance 500 mg/2.5 mg and Glucovance 5...
peer reviewedADOPT ("A Diabetes Outcome Progression Trial") is a double-blind, controlled clinical t...
Sodium-glucose cotransporter 2 (SGLT2) inhibitors are a class of drugs which offer cardiovascular (C...
peer reviewedBeyond lifestyle changes, the management of type 2 diabetes comprises the administratio...
peer reviewedType 2 diabetes (T2D) is a complex disease with multiple defects, which generally requi...
peer reviewedThe diabetic patient, when type 2 diabetes is newly diagnosed, raises a therapeutic pro...
peer reviewedType 2 diabetes is a complex disease characterized by a dual defect of insulin secretio...
peer reviewedType 2 diabetes is a complex disease combining several disturbances in various organs, ...
peer reviewedExenatide (Byetta) is a synthetic derivative of exendin-4 and an agonist of receptors o...
peer reviewedGlucagon-like peptide-1 (GLP-1) is a gut hormone secreted in response to the ingestion ...
peer reviewedKidney plays a role in glucose homeostasis, not only by its capacity to produce glucose...
peer reviewedIn a patient with type 2 diabetes not well controlled with a basal insulin - metformin ...
Insulin therapy, often initiated after hygiene and dietary measures and non-insulin antidiabetics, i...
peer reviewedManagement of type 1 diabetes essentially relies upon intensive insulin therapy adjuste...
peer reviewedType 1 diabetes (T1D) management is still complex. Some drugs have been proposed as adj...
peer reviewedGlucovance, recently launched by Merck-Lipha (Glucovance 500 mg/2.5 mg and Glucovance 5...
peer reviewedADOPT ("A Diabetes Outcome Progression Trial") is a double-blind, controlled clinical t...
Sodium-glucose cotransporter 2 (SGLT2) inhibitors are a class of drugs which offer cardiovascular (C...
peer reviewedBeyond lifestyle changes, the management of type 2 diabetes comprises the administratio...