Ribulose 5-phosphate (Ru5P) and guanosine 5′-triphosphate (GTP) are two key precursors of riboflavin, whereby Ru5P is also a precursor of GTP. Ribulose 5-phosphate 3-epimerase (Rpe) catalyzes the conversion of ribulose 5-phosphate into xylulose 5-phosphate. Inactivation of Rpe can reduce the consumption of Ru5P, enhancing the carbon flux toward riboflavin biosynthesis. Here we investigated the effect of mutation of rpe and other related genes on riboflavin production, physiological and metabolic phenotypes in Bacillus subtilis LY (BSLY). Introducing single nucleotide deletion (generated BSR) or nonsense mutation (generated BSRN) on the genomic copy of rpe, resulting in more than fivefold increase of riboflavin production over the parental s...
Abstract Background Riboflavin, an intermediate of primary metabolism, is one kind of important food...
Riboflavin or vitamin B2 is a water-soluble vitamin and a precursor of flavin coenzymes, flavin mono...
Riboflavin (vitamin B2) is one of the B-group water-soluble vitamins and is essential for energy met...
We generated a high riboflavin-producing mutant strain of Ashbya gossypii by disparity mutagenesis u...
A mutation leading to roseoflavin resistance and deregulated riboflavin biosynthesis was mapped in t...
Chemical riboflavin production, successfully used for decades, is in the course of being replaced by...
Riboflavin is an essential micronutrient for humans and must be obtained exogenously from foods or s...
Riboflavin (Vitamin B2) is one of the essential vitamins required by humans and higher animals that ...
Riboflavin synthase (RiS) is a homotrimeric enzyme that catalyzes the final reaction of riboflavin (...
Kissling L, Schneider C, Seibel K, et al. The roseoflavin producer Streptomyces davaonensis has a hi...
BACKGROUND: D-ribose, a five carbon sugar, can be produced via mutant strains with impairment in the...
Background: Ribonucleases (RNases) can be used in both basic and clinical sciences, e.g. in research...
17 p.-6 fig.-1 tab.Manufacturing of probiotics and functional foods using lactic acid bacteria (LAB)...
The production of riboflavin from vegetable oil was increased using a mutant strain of Ashbya gossyp...
The investigation of new secretory ribonucleases, the Bacillus intermedius binase II expressed in th...
Abstract Background Riboflavin, an intermediate of primary metabolism, is one kind of important food...
Riboflavin or vitamin B2 is a water-soluble vitamin and a precursor of flavin coenzymes, flavin mono...
Riboflavin (vitamin B2) is one of the B-group water-soluble vitamins and is essential for energy met...
We generated a high riboflavin-producing mutant strain of Ashbya gossypii by disparity mutagenesis u...
A mutation leading to roseoflavin resistance and deregulated riboflavin biosynthesis was mapped in t...
Chemical riboflavin production, successfully used for decades, is in the course of being replaced by...
Riboflavin is an essential micronutrient for humans and must be obtained exogenously from foods or s...
Riboflavin (Vitamin B2) is one of the essential vitamins required by humans and higher animals that ...
Riboflavin synthase (RiS) is a homotrimeric enzyme that catalyzes the final reaction of riboflavin (...
Kissling L, Schneider C, Seibel K, et al. The roseoflavin producer Streptomyces davaonensis has a hi...
BACKGROUND: D-ribose, a five carbon sugar, can be produced via mutant strains with impairment in the...
Background: Ribonucleases (RNases) can be used in both basic and clinical sciences, e.g. in research...
17 p.-6 fig.-1 tab.Manufacturing of probiotics and functional foods using lactic acid bacteria (LAB)...
The production of riboflavin from vegetable oil was increased using a mutant strain of Ashbya gossyp...
The investigation of new secretory ribonucleases, the Bacillus intermedius binase II expressed in th...
Abstract Background Riboflavin, an intermediate of primary metabolism, is one kind of important food...
Riboflavin or vitamin B2 is a water-soluble vitamin and a precursor of flavin coenzymes, flavin mono...
Riboflavin (vitamin B2) is one of the B-group water-soluble vitamins and is essential for energy met...