Predictors of first-year nonadherence and discontinuation of statins among older adults: a retrospective cohort study
- Ofori-Asenso, R
- Ilomaeki, J
- Tacey, M
- Si, S
- Curtis, AJ
- Zomer, E
- Bell, JS
- Zoungas, S
- Liew, D
DOIAbstract
AIMS: The aim of this study was to examine the level of and predictors of statin nonadherence and discontinuation among older adults. METHODS: Among 22 340 Australians aged ≥65 years who initiated statin therapy from January 2014 to December 2015, we estimated the first-year nonadherence (proportion of days covered [PDC] <0.80) and discontinuation (≥90 days without statin coverage) rates. Predictors of nonadherence and discontinuation were examined via multivariable logistic regression. Analyses were performed separately for general beneficiaries (with a higher co-payment; n = 4841) and concessional beneficiaries (with a lower co-payment; n = 17 499). RESULTS: During the one-year follow-up, 55.1% were nonadherent (concessional 52.6%; genera...
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