This chapter discussed the digital library and distance learning benefits and challenges in developing countries. It started with the general introduction of digital library and distance learning, and went further and discussed the nexus between the digital library and distance learning. The chapter further highlighted the benefits of digital library in distance learning. It also pointed out the challenges of distance learning in developing countries, such as finance, lack of conducive learning environment, poor policies on education, inadequate instructional materials, among others. The chapter further discussed the challenges of digital library in developing countries to include insufficient funding, high cost of instructional materials, ...