Chlamydia trachomatis is a common sexually transmitted infection that is associated with a range of serious reproductive tract sequelae including in women Pelvic Inflammatory Disease (PID), tubal factor infertility, and ectopic pregnancy. Ascension of the pathogen beyond the cervix and into the upper reproductive tract is thought to be necessary for these pathologies. However, Chlamydia trachomatis does not encode a mechanism for movement on its genome, and so the processes that facilitate ascension have not been elucidated. Here, we evaluate the factors that may influence chlamydial ascension in women. We constructed a mathematical model based on a set of stochastic dynamics to elucidate the moderating factors that might influence ascensio...
Chlamydiae are intracellular bacterial parasites that develop and multiply within mucosal cells of h...
Chlamydia infection remains the leading sexually-transmitted bacterial infection worldwide, causing ...
PMCID: PMC3505463The electronic version of this article is the complete one and can be found online ...
Sexually transmitted chlamydial infection initially establishes in the endocervix in females, but if...
Sexually transmitted chlamydial infection initially establishes in the endocervix in females, but if...
Chlamydia trachomatis infections have been implicated in problems such as pelvic inflammatory diseas...
Chlamydia trachomatis is a bacterial pathogen that can cause serious reproductive harm. We describe ...
© 2015, American Society for Microbiology. All Rights Reserved. Chlamydia trachomatis is the most co...
Objective: To develop a model of pathogenesis by which Chlamydia trachomatis progresses from acute t...
Free to read Chlamydia trachomatis is the most common bacterial sexually transmitted pathogen worldw...
Chlamydia trachomatis is the most common bacterial sexually transmitted pathogen worldwide. Infectio...
Critical to evaluating Chlamydia trachomatis vaccine candidates is the availability of appropriate a...
Sexually transmitted infections with Chlamydia trachomatis are highly prevalent and can lead to irre...
Chlamydia are bacterial pathogens of humans and animals causing the important human diseases trachom...
Critical to evaluating Chlamydia trachomatis vaccine candidates is the availability of appropriate a...
Chlamydiae are intracellular bacterial parasites that develop and multiply within mucosal cells of h...
Chlamydia infection remains the leading sexually-transmitted bacterial infection worldwide, causing ...
PMCID: PMC3505463The electronic version of this article is the complete one and can be found online ...
Sexually transmitted chlamydial infection initially establishes in the endocervix in females, but if...
Sexually transmitted chlamydial infection initially establishes in the endocervix in females, but if...
Chlamydia trachomatis infections have been implicated in problems such as pelvic inflammatory diseas...
Chlamydia trachomatis is a bacterial pathogen that can cause serious reproductive harm. We describe ...
© 2015, American Society for Microbiology. All Rights Reserved. Chlamydia trachomatis is the most co...
Objective: To develop a model of pathogenesis by which Chlamydia trachomatis progresses from acute t...
Free to read Chlamydia trachomatis is the most common bacterial sexually transmitted pathogen worldw...
Chlamydia trachomatis is the most common bacterial sexually transmitted pathogen worldwide. Infectio...
Critical to evaluating Chlamydia trachomatis vaccine candidates is the availability of appropriate a...
Sexually transmitted infections with Chlamydia trachomatis are highly prevalent and can lead to irre...
Chlamydia are bacterial pathogens of humans and animals causing the important human diseases trachom...
Critical to evaluating Chlamydia trachomatis vaccine candidates is the availability of appropriate a...
Chlamydiae are intracellular bacterial parasites that develop and multiply within mucosal cells of h...
Chlamydia infection remains the leading sexually-transmitted bacterial infection worldwide, causing ...
PMCID: PMC3505463The electronic version of this article is the complete one and can be found online ...