The corneal endothelium is the innermost layer of the cornea that selectively pumps ions and metabolites and regulates the hydration level of the cornea, ensuring its transparency. Trauma or disease affecting human corneal endothelial cells (hCECs) can result in major imbalances of such transport activity with consequent deterioration or loss of vision. Since tissue transplantation from deceased donors is only available to a fraction of patients worldwide, alternative solutions are urgently needed. Cell therapy approaches, in particular by attempting to expand primary culture of hCECs in vitro, aim to tackle this issue. However, existing cell culture protocols result in limited expansion of this cell type. Recent studies in this field have ...
Background: Endothelium allotransplantation is the primary treatment for corneal decompensation. The...
International audienceThe posterior side of the cornea is covered by the endothelial monolayer, whic...
Abstract: Human corneal endothelial cells (HCECs) do not replicate after wounding. Therefore, cornea...
The corneal endothelium is the innermost layer of the cornea that selectively pumps ions and metabol...
Abstract Corneal endothelial cells (CECs) have limited proliferation ability leading to corneal end...
Corneal endothelium is a single layer of specialized cells that lines the posterior surface of corne...
The corneal endothelium is the posterior monolayer of cells that are responsible for maintaining ove...
[[abstract]]Objective: To investigate whether the bioengineered human corneal endothelial cell (HCEC...
Abstract: Corneal endothelium is a single layer of specialized cells that lines the posterior surfac...
International audienceThe cornea is a multi-layered structure which allows fine refraction and provi...
The demand for corneal tissue for transplantation is not fully supplied, forcing the harvesting of c...
Abstract Human corneal endothelial cells are notorious for their restricted proliferative ability in...
Corneal transplantation is currently the only effective treatment option for dysfunctional corneal e...
Corneal endothelial (CE) cells do not divide in vivo, leading to edema, corneal clouding and vision ...
The barrier and pump functions of the corneal endothelium are essential for the maintenance of corne...
Background: Endothelium allotransplantation is the primary treatment for corneal decompensation. The...
International audienceThe posterior side of the cornea is covered by the endothelial monolayer, whic...
Abstract: Human corneal endothelial cells (HCECs) do not replicate after wounding. Therefore, cornea...
The corneal endothelium is the innermost layer of the cornea that selectively pumps ions and metabol...
Abstract Corneal endothelial cells (CECs) have limited proliferation ability leading to corneal end...
Corneal endothelium is a single layer of specialized cells that lines the posterior surface of corne...
The corneal endothelium is the posterior monolayer of cells that are responsible for maintaining ove...
[[abstract]]Objective: To investigate whether the bioengineered human corneal endothelial cell (HCEC...
Abstract: Corneal endothelium is a single layer of specialized cells that lines the posterior surfac...
International audienceThe cornea is a multi-layered structure which allows fine refraction and provi...
The demand for corneal tissue for transplantation is not fully supplied, forcing the harvesting of c...
Abstract Human corneal endothelial cells are notorious for their restricted proliferative ability in...
Corneal transplantation is currently the only effective treatment option for dysfunctional corneal e...
Corneal endothelial (CE) cells do not divide in vivo, leading to edema, corneal clouding and vision ...
The barrier and pump functions of the corneal endothelium are essential for the maintenance of corne...
Background: Endothelium allotransplantation is the primary treatment for corneal decompensation. The...
International audienceThe posterior side of the cornea is covered by the endothelial monolayer, whic...
Abstract: Human corneal endothelial cells (HCECs) do not replicate after wounding. Therefore, cornea...