Add to ORKGThe ploidy of human bone marrow cells belonging to the megakaryocytic, granulocytic-monocytic and erythrocytic lineages was studied by in situ hybridization using the biotin-labelled Y chromosome-specific DNA probe pY431 and the chromosome 1-specific probe pUC1.77 on cells identified morphologically and immunologically by the MAC procedure. Cells of the granulocytic-monocytic and erythrocytic lineages were seen to be 2N in ploidy, whereas the ploidy of the megakaryocytic lineage ranged from 2N to 32N, with the ploidy classes 4N and 8N being predominant. The frequency of megakaryocytes with 2N chromosomes was also high.Facultad de Ciencias Naturales y Muse
system for human peripheral blood megakaryocyte colony-forming unit cells (CFU-M) using an anti-plat...
Six patients, five with acute myeloid leukemia (AML) and one with a myelodysplastic syndrome (MDS), ...
The aim of the study was an estimation of the histomorphometry of megakaryocytes (MK) in bone marrow...
To investigate megakaryocyte (MK) DNA ploidy in various hematological diseases, fluorescence microsc...
Background Recent advances in single-cell techniques have provided the opportunity to finely dissect...
Megakaryocytes are large, distinctive cells found mainly in the bone marrow. They produce platelets ...
Cytogenetic analysis of fresh marrow provides an assessment primarily of the distribution of karyoty...
Background: Megakaryocytes (MKs) originate from cells immuno-phenotypically indistinguishable from h...
We reviewed the literature concerning the history of determination of the ploidy of human megakaryoc...
BACKGROUND AND OBJECTIVES: A pluripotent progenitor cell was demonstrated to be involved in myelodys...
In most neoplasms malignant change occurs in a single cell which then proliferates. My purpose was t...
Chromosomal in situ suppression (CISS) hybridization was performed with library DNA from sorted huma...
Cytogenetic analysis of the malignant clone is clinically important in haematological malignancy. A...
Flow cytometry was used to measure the fluorescence intensity of nuclei that were subjected to fluor...
system for human peripheral blood megakaryocyte colony-forming unit cells (CFU-M) using an anti-plat...
Six patients, five with acute myeloid leukemia (AML) and one with a myelodysplastic syndrome (MDS), ...
The aim of the study was an estimation of the histomorphometry of megakaryocytes (MK) in bone marrow...
To investigate megakaryocyte (MK) DNA ploidy in various hematological diseases, fluorescence microsc...
Background Recent advances in single-cell techniques have provided the opportunity to finely dissect...
Megakaryocytes are large, distinctive cells found mainly in the bone marrow. They produce platelets ...
Cytogenetic analysis of fresh marrow provides an assessment primarily of the distribution of karyoty...
Background: Megakaryocytes (MKs) originate from cells immuno-phenotypically indistinguishable from h...
We reviewed the literature concerning the history of determination of the ploidy of human megakaryoc...
BACKGROUND AND OBJECTIVES: A pluripotent progenitor cell was demonstrated to be involved in myelodys...
In most neoplasms malignant change occurs in a single cell which then proliferates. My purpose was t...
Chromosomal in situ suppression (CISS) hybridization was performed with library DNA from sorted huma...
Cytogenetic analysis of the malignant clone is clinically important in haematological malignancy. A...
Flow cytometry was used to measure the fluorescence intensity of nuclei that were subjected to fluor...
system for human peripheral blood megakaryocyte colony-forming unit cells (CFU-M) using an anti-plat...
Six patients, five with acute myeloid leukemia (AML) and one with a myelodysplastic syndrome (MDS), ...
The aim of the study was an estimation of the histomorphometry of megakaryocytes (MK) in bone marrow...