Aim: DNA damage associated with Oral Squamous Cell Carcinoma (OSCC) and potentially malignant disorders (PMDs) is produced due to carcinogenic agents or increased oxidative stress. Comet assay can assist in early detection and evaluation of the amount of DNA damage; lymphocytesare the most commonly used cells for performing comet assay. Utilisation of buccal epithelial cells in comet assay can be a minimally invasive and rapid method. The present study compared the efficacy of comet assay in assessing DNA damage in buccal cells over peripheral blood leucocytes (PBLs) in oral potentially malignant and malignant disorders. Methods: The study included fifty five patients each of Leukoplakia, Oral Submucous Fibrosis (OSMF) and OSCC along with ...
The comet assay is widely used for quantification of genomic damage in humans. Peripheral blood deri...
Objective: To elucidate whether DNA aneuploidy was an independent discriminator for carcinoma within...
The comet assay or single cell gel electrophoresis, is the most common method used to measure strand...
DNA damage risk assessment in comet assay by the use of buccal mucosa cells has great advantages in ...
BACKGROUND: The use of tobacco continues to be the leading preventable cause of death in the world...
BACKGROUND: Oral submucous fibrosis (OSF) is one of the potentially malignant disorders with a hig...
The comet assay is a widely used biomonitoring tool for DNA damage. The most commonly used cells in ...
Background: The term oral potentially malignant disorder (OPMD) was recommended to refer to precance...
Ionizing radiation (IR) presents a risk to human health via DNA damage even when administered at low...
Background: X-rays are potential mutagenic agents that can cause both the gene mutations and chromos...
Background: Cytogenic methods acts with complex type mutations, known as structural mutations (aberr...
Oral cancer is a progressive, multistage disease in which changes in genetic structure and cellular ...
This study aimed to evaluate DNA damage in patients with breast cancer before treatment (background)...
Context: Micronucleus (MN) has been proved to be an important biomarker of genomic damage. MN scorin...
Background and Objective: Periodontal disease is a chronic bacterial infection characterized by conn...
The comet assay is widely used for quantification of genomic damage in humans. Peripheral blood deri...
Objective: To elucidate whether DNA aneuploidy was an independent discriminator for carcinoma within...
The comet assay or single cell gel electrophoresis, is the most common method used to measure strand...
DNA damage risk assessment in comet assay by the use of buccal mucosa cells has great advantages in ...
BACKGROUND: The use of tobacco continues to be the leading preventable cause of death in the world...
BACKGROUND: Oral submucous fibrosis (OSF) is one of the potentially malignant disorders with a hig...
The comet assay is a widely used biomonitoring tool for DNA damage. The most commonly used cells in ...
Background: The term oral potentially malignant disorder (OPMD) was recommended to refer to precance...
Ionizing radiation (IR) presents a risk to human health via DNA damage even when administered at low...
Background: X-rays are potential mutagenic agents that can cause both the gene mutations and chromos...
Background: Cytogenic methods acts with complex type mutations, known as structural mutations (aberr...
Oral cancer is a progressive, multistage disease in which changes in genetic structure and cellular ...
This study aimed to evaluate DNA damage in patients with breast cancer before treatment (background)...
Context: Micronucleus (MN) has been proved to be an important biomarker of genomic damage. MN scorin...
Background and Objective: Periodontal disease is a chronic bacterial infection characterized by conn...
The comet assay is widely used for quantification of genomic damage in humans. Peripheral blood deri...
Objective: To elucidate whether DNA aneuploidy was an independent discriminator for carcinoma within...
The comet assay or single cell gel electrophoresis, is the most common method used to measure strand...