Constructing valid super-resolution intact genome 3D structures from single-cell Hi-C data is essential in investigating chromosome folding. Here the authors develop a method that makes it possible to visualize and investigate chromosome folding in individual cells at the genome scal
Chromosome conformation capture-based methods such as Hi-C have become mainstream techniques for the...
The 3D organization of eukaryotic chromosomes affects key processes such as gene expression, DNA rep...
While we often think of the genome as a linear object, in reality chromosomes are folded in a highly...
In recent years researchers have begun to reveal the hierarchy of mammalian DNA folding from the 10 ...
Single-cell chromosome conformation capture approaches are revealing the extent of cell-to-cell vari...
International audienceOver the past two decades, the development of chromosome conformation capture ...
Summary: 3D genome structure is highly heterogeneous among single cells and contributes to cellular ...
<p>Single-cell chromosome conformation capture approaches are revealing the extent of cell-to-cell v...
We present Micro-C XL, an improved method for analysis of chromosome folding at mononucleosome resol...
Chromosome conformation capture-based methods such as Hi-C have become mainstream techniques for the...
The three-dimensional folding of chromosomes compartmentalizes the genome and and can bring distant ...
We describe a method, Hi-C, to comprehensively detect chromatin interactions in the mammalian nucleu...
SummaryWe describe a Hi-C-based method, Micro-C, in which micrococcal nuclease is used instead of re...
The ability to decipher the three-dimensional chromosome folding in many eukaryotes is a major asset...
The intricate folding of chromatin enables living organisms to store genomic material in an extremel...
Chromosome conformation capture-based methods such as Hi-C have become mainstream techniques for the...
The 3D organization of eukaryotic chromosomes affects key processes such as gene expression, DNA rep...
While we often think of the genome as a linear object, in reality chromosomes are folded in a highly...
In recent years researchers have begun to reveal the hierarchy of mammalian DNA folding from the 10 ...
Single-cell chromosome conformation capture approaches are revealing the extent of cell-to-cell vari...
International audienceOver the past two decades, the development of chromosome conformation capture ...
Summary: 3D genome structure is highly heterogeneous among single cells and contributes to cellular ...
<p>Single-cell chromosome conformation capture approaches are revealing the extent of cell-to-cell v...
We present Micro-C XL, an improved method for analysis of chromosome folding at mononucleosome resol...
Chromosome conformation capture-based methods such as Hi-C have become mainstream techniques for the...
The three-dimensional folding of chromosomes compartmentalizes the genome and and can bring distant ...
We describe a method, Hi-C, to comprehensively detect chromatin interactions in the mammalian nucleu...
SummaryWe describe a Hi-C-based method, Micro-C, in which micrococcal nuclease is used instead of re...
The ability to decipher the three-dimensional chromosome folding in many eukaryotes is a major asset...
The intricate folding of chromatin enables living organisms to store genomic material in an extremel...
Chromosome conformation capture-based methods such as Hi-C have become mainstream techniques for the...
The 3D organization of eukaryotic chromosomes affects key processes such as gene expression, DNA rep...
While we often think of the genome as a linear object, in reality chromosomes are folded in a highly...