Comment on: Very-Low-Calorie Ketogenic Diet as a Safe and Valuable Tool for Long-Term Glycemic Management in Patients with Obesity and Type 2 Diabetes

With interest, we have read the article of Moriconi et al entitled “Very-Low-Calorie Ketogenic Diet as a Safe and Valuable Tool for Long-Term Glycemic Management in Patients with Obesity and Type 2 Diabetes.” A very low carbohydrate ketogenic diet is a popular, often effective dietary intervention for people with obesity related-type 2 diabetes mellitus (T2DM). However, ketogenic diets applied in T2DM studies differ significantly in nutrient composition (different percentages of carbohydrate, protein, fat and types of fatty acids), resulting in a heterogeneity that influences reproducibility and interpretation of their results. [...