Background: Insulin resistance (IR), a key characteristic of type 2 diabetes (T2DM), is manifested by decreased insulin-stimulated glucose transport in target tissues. Emerging research has highlighted transient receptor potential cation channel subfamily V member (TRPV1) activation by capsaicin as a potential therapeutic target for these conditions. However, there are limited data on the effects of capsaicin on cell signalling molecules involved in glucose uptake. Methods: C2C12 cells were cultured and differentiated to acquire the myotube phenotype. The activation status of signalling molecules involved in glucose metabolism, including 5’ adenosine monophosphate-activated protein kinase (AMPK), calcium/calmodulin-dependent protein kinase ...
OBJECTIVE—TRPM2 is a Ca2-permeable nonselective cation channel activated by adenosine dinucleotides....
Mechanical load-induced intracellular signaling events are important for subsequent skeletal muscle ...
In insulin-sensitive skeletal muscle, the expression of constitutively active Ca2+/calmodulin-depend...
Background: Insulin resistance (IR), a key characteristic of type 2 diabetes (T2DM), is manifested b...
Background: Insulin resistance (IR), a key characteristic of type 2 diabetes (T2DM), is manifested b...
Our previous research showed that capsaicin exhibits hypoglycemic effects by activating the transien...
Capsaicin and zinc have recently been highlighted as potential treatments for glucose metabolism dis...
Capsaicin and zinc have recently been highlighted as potential treatments for glucose metabolism dis...
Introduction: Diabetic peripheral neuropathy is a common chronic complic ation of diabetes mellitus....
Diabetic peripheral neuropathy is a common chronic complica-tion of diabetes mellitus. Transient rec...
Signalling pathways play a critical role in a range of metabolic processes including glucose metabol...
Pharmacological therapies in type 1 diabetes for efficient control of glycemia and changes in pain a...
Obesity is a major metabolic disease. Currently, there are no effective strategies to counter obesit...
Capsaicin, the major active constituent of chilli, is an agonist on transient receptor potential van...
Capsaicin, the major active constituent of chilli, is an agonist on transient receptor potential van...
OBJECTIVE—TRPM2 is a Ca2-permeable nonselective cation channel activated by adenosine dinucleotides....
Mechanical load-induced intracellular signaling events are important for subsequent skeletal muscle ...
In insulin-sensitive skeletal muscle, the expression of constitutively active Ca2+/calmodulin-depend...
Background: Insulin resistance (IR), a key characteristic of type 2 diabetes (T2DM), is manifested b...
Background: Insulin resistance (IR), a key characteristic of type 2 diabetes (T2DM), is manifested b...
Our previous research showed that capsaicin exhibits hypoglycemic effects by activating the transien...
Capsaicin and zinc have recently been highlighted as potential treatments for glucose metabolism dis...
Capsaicin and zinc have recently been highlighted as potential treatments for glucose metabolism dis...
Introduction: Diabetic peripheral neuropathy is a common chronic complic ation of diabetes mellitus....
Diabetic peripheral neuropathy is a common chronic complica-tion of diabetes mellitus. Transient rec...
Signalling pathways play a critical role in a range of metabolic processes including glucose metabol...
Pharmacological therapies in type 1 diabetes for efficient control of glycemia and changes in pain a...
Obesity is a major metabolic disease. Currently, there are no effective strategies to counter obesit...
Capsaicin, the major active constituent of chilli, is an agonist on transient receptor potential van...
Capsaicin, the major active constituent of chilli, is an agonist on transient receptor potential van...
OBJECTIVE—TRPM2 is a Ca2-permeable nonselective cation channel activated by adenosine dinucleotides....
Mechanical load-induced intracellular signaling events are important for subsequent skeletal muscle ...
In insulin-sensitive skeletal muscle, the expression of constitutively active Ca2+/calmodulin-depend...