The SARS-CoV-2 outbreak is characterized by the need of the search for curative drugs for treatment. In this paper, we present an update of knowledge about the interest of the functional inhibitors of acid sphingomyelinase (FIASMAs) in SARS-CoV-2 infection. Forty-nine FIASMAs have been suggested in the treatment of SARS-CoV-2 infection using in silico, in vitro or in vivo studies. Further studies using large-sized, randomized and double-blinded controlled clinical trials are needed to evaluate FIASMAs in SARS-CoV-2 infection as off-label therapy.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
The main protease (Mpro) plays a crucial role in severe acute respiratory syndrome coronavirus 2 (SA...
In 2019 an outbreak occurred which resulted in a global pandemic. The causative agent has been ident...
Since the outbreak of COVID-19, one of the strategies used to search for new drugs has been to find ...
The SARS-CoV-2 outbreak is characterized by the need of the search for curative drugs for treatment....
International audienceWHAT IS KNOWN AND OBJECTIVE: Infection by SARS-CoV-2, the virus responsible of...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the COVID-19 pandemic w...
We describe a hitherto unknown feature for 27 small drug-like molecules, namely functional inhibitio...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the COVID-19 pandemic w...
The rapid spread of COVID-19 has become a health emergency causing an urgent need for drug treatment...
We describe a hitherto unknown feature for 27 small drug-like molecules, namely functional inhibitio...
National audienceGiven the current scarcity of curative treatment of COVID-19, the search for an eff...
[[abstract]]Severe Acute Respiratory Syndrome (SARS) is a life-threatening infectious disease caused...
Acid Sphingomyelinase (ASM) is a human phosphodiesterase that catalyzes the metabolism of sphingomye...
Acid Sphingomyelinase (ASM) is a human phosphodiesterase that catalyzes the metabolism of sphingomye...
Effective treatment strategies for severe coronavirus disease (COVID-19) remain scarce. Hydrolysis o...
The main protease (Mpro) plays a crucial role in severe acute respiratory syndrome coronavirus 2 (SA...
In 2019 an outbreak occurred which resulted in a global pandemic. The causative agent has been ident...
Since the outbreak of COVID-19, one of the strategies used to search for new drugs has been to find ...
The SARS-CoV-2 outbreak is characterized by the need of the search for curative drugs for treatment....
International audienceWHAT IS KNOWN AND OBJECTIVE: Infection by SARS-CoV-2, the virus responsible of...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the COVID-19 pandemic w...
We describe a hitherto unknown feature for 27 small drug-like molecules, namely functional inhibitio...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the COVID-19 pandemic w...
The rapid spread of COVID-19 has become a health emergency causing an urgent need for drug treatment...
We describe a hitherto unknown feature for 27 small drug-like molecules, namely functional inhibitio...
National audienceGiven the current scarcity of curative treatment of COVID-19, the search for an eff...
[[abstract]]Severe Acute Respiratory Syndrome (SARS) is a life-threatening infectious disease caused...
Acid Sphingomyelinase (ASM) is a human phosphodiesterase that catalyzes the metabolism of sphingomye...
Acid Sphingomyelinase (ASM) is a human phosphodiesterase that catalyzes the metabolism of sphingomye...
Effective treatment strategies for severe coronavirus disease (COVID-19) remain scarce. Hydrolysis o...
The main protease (Mpro) plays a crucial role in severe acute respiratory syndrome coronavirus 2 (SA...
In 2019 an outbreak occurred which resulted in a global pandemic. The causative agent has been ident...
Since the outbreak of COVID-19, one of the strategies used to search for new drugs has been to find ...