Dietary intake of n-3 long-chain polyunsaturated fatty acids and risk of myocardial infarction in coronary artery disease patients with or without diabetes mellitus: a prospective cohort study
- Strand, Elin
- Pedersen, Eva Kristine Ringdal
- Svingen, Gard Frodahl Tveitevåg
- Schartum-Hansen, Hall
- Rebnord, Eirik Wilberg
- Bjørndal, Bodil
- Seifert, Reinhard
- Bohov, Pavol
- Meyer, Klaus
- Hiltunen, J. Kalervo
- Nordrehaug, Jan Erik
- Nilsen, Dennis W. T.
- Berge, Rolf Kristian
- Nygård, Ottar
DOIAbstract
Background: A beneficial effect of a high n-3 long-chain polyunsaturated fatty acid (LCPUFA) intake has been observed in heart failure patients, who are frequently insulin resistant. We investigated the potential influence of impaired glucose metabolism on the relation between dietary intake of n-3 LCPUFAs and risk of acute myocardial infarction (AMI) in patients with coronary artery disease. Methods: This prospective cohort study was based on the Western Norway B-Vitamin Intervention Trial and included 2,378 patients with coronary artery disease with available baseline glycosylated hemoglobin (HbA1c) and dietary data. Patients were sub-grouped as having no diabetes (HbA1c <5.7%), pre-diabetes (HbA1c ≥5.7%), or diabetes (previous diabetes, ...
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