Copper ions are found in a number of enzyme active sites that facilitate many biologically important reactions such as dioxygen activation and bacterial denitrification. These enzyme catalyzed reactions proceed extremely fast in aqueous media and reaction mechanisms are largely unknown. Inspired by these enzymatic reactions and employing coordination chemistry with ligand copper complexes in organic solvents, we can study the formation and reactivity of room temperature unstable copper-O2/NO adducts that became meta-stable at much lower temperature. For the system we describe here, a phenol-containing binucleating ligand (UN-O–) is employed, giving rise to a series of phenolate-bridged dicopper complexes of various types. A structurally cha...
This thesis focuses on the activation of small molecules by dinuclear copper complexes. Initially, i...
Our long-time niche in synthetic biological inorganic chemistry has been to design ligands and gener...
Oxygenation of copper(I) with tetradentate tripodal ligands (L) comprised of a tris(aminoethyl)amine...
The reductive activation of dioxygen, which is often coupled to other processes such as substrate hy...
The intricacies of metalloprotein chemistry including the fundamentally important mechanistic detail...
The investigation into the chemical/physical properties of synthetic copper complexes provide fundam...
The study of suitably designed synthetic models can lead to fundamental chemical insights for enzyme...
The reductive activation of dioxygen, which is often coupled to other processes such as substrate hy...
Nitric oxide (NO•) plays a multifaceted role in chemistry and biology and is recognized as an import...
Enzymes where the active site contains one or more copper ions catalyze a wide range of organic subs...
Synthetic bioinorganic chemistry has played a crucial role in the understanding of fundamental aspec...
Dinuclear copper assemblies are encountered in the active centers of various oxidases involved in th...
Dinuclear copper assemblies are encountered in the active centers of various oxidases involved in th...
Dioxygen is widely used in nature as oxidant. Nature itself has served as inspiration to use O-2 in ...
Transition metal-dioxygen (O2) interactions are of great importance in biological and chemical trans...
This thesis focuses on the activation of small molecules by dinuclear copper complexes. Initially, i...
Our long-time niche in synthetic biological inorganic chemistry has been to design ligands and gener...
Oxygenation of copper(I) with tetradentate tripodal ligands (L) comprised of a tris(aminoethyl)amine...
The reductive activation of dioxygen, which is often coupled to other processes such as substrate hy...
The intricacies of metalloprotein chemistry including the fundamentally important mechanistic detail...
The investigation into the chemical/physical properties of synthetic copper complexes provide fundam...
The study of suitably designed synthetic models can lead to fundamental chemical insights for enzyme...
The reductive activation of dioxygen, which is often coupled to other processes such as substrate hy...
Nitric oxide (NO•) plays a multifaceted role in chemistry and biology and is recognized as an import...
Enzymes where the active site contains one or more copper ions catalyze a wide range of organic subs...
Synthetic bioinorganic chemistry has played a crucial role in the understanding of fundamental aspec...
Dinuclear copper assemblies are encountered in the active centers of various oxidases involved in th...
Dinuclear copper assemblies are encountered in the active centers of various oxidases involved in th...
Dioxygen is widely used in nature as oxidant. Nature itself has served as inspiration to use O-2 in ...
Transition metal-dioxygen (O2) interactions are of great importance in biological and chemical trans...
This thesis focuses on the activation of small molecules by dinuclear copper complexes. Initially, i...
Our long-time niche in synthetic biological inorganic chemistry has been to design ligands and gener...
Oxygenation of copper(I) with tetradentate tripodal ligands (L) comprised of a tris(aminoethyl)amine...