Clearance of viral infections, such as SARS-CoV-2 and influenza A virus (IAV), must be fine-tuned to eliminate the pathogen without causing immunopathology. As such, an aggressive initial innate immune response favors the host in contrast to a detrimental prolonged inflammation. The complement pathway bridges innate and adaptive immune system and contributes to the response by directly clearing pathogens or infected cells, as well as recruiting proinflammatory immune cells and regulating inflammation. However, the impact of modulating complement activation in viral infections is still unclear. In this work, we targeted the complement decay-accelerating factor (DAF/CD55), a surface protein that protects cells from non-specific complement att...
The complement cascade defines an important link between the innate and the specific immune system. ...
12 p.- 3 fig.- 2 tab.The surveillance and pathogen fighting functions of the complement system have ...
There is considerable evidence that influenza A virus (IAV) promotes adherence, colonization, and su...
Clearance of viral infections, such as SARS-CoV-2 and influenza A virus (IAV), must be fine-tuned to...
"The complement system is a key component of the immune response as it bridges innate and adaptive ...
Influenza virus A (IAV) causes annual epidemics and intermittent pandemics that affect millions of p...
Influenza virus A (IAV) causes annual epidemics and intermittent pandemics that affect millions of p...
Copyright © 2020 Murugaiah, Varghese, Saleh, Tsolaki, Alrokayan, Khan, Collison, Sim, Nal, Al-Mohann...
Highly pathogenic H5N1 influenza infections are associated with enhanced inflammatory and cytokine r...
The respiratory tract pathogen Haemophilus influenzae is responsible for a variety of infections in ...
Background: Viral infection including pandemic influenza may be associated with severe acute respira...
There is considerable evidence that influenza A virus (IAV) promotes adherence, colonization, and su...
International audienceThe complement system is designed to recognise and eliminate invading pathogen...
AbstractThe complement system functions as an immune surveillance system that rapidly responds to in...
To improve COVID-19 therapy, it is essential to understand the mechanisms driving critical illness. ...
The complement cascade defines an important link between the innate and the specific immune system. ...
12 p.- 3 fig.- 2 tab.The surveillance and pathogen fighting functions of the complement system have ...
There is considerable evidence that influenza A virus (IAV) promotes adherence, colonization, and su...
Clearance of viral infections, such as SARS-CoV-2 and influenza A virus (IAV), must be fine-tuned to...
"The complement system is a key component of the immune response as it bridges innate and adaptive ...
Influenza virus A (IAV) causes annual epidemics and intermittent pandemics that affect millions of p...
Influenza virus A (IAV) causes annual epidemics and intermittent pandemics that affect millions of p...
Copyright © 2020 Murugaiah, Varghese, Saleh, Tsolaki, Alrokayan, Khan, Collison, Sim, Nal, Al-Mohann...
Highly pathogenic H5N1 influenza infections are associated with enhanced inflammatory and cytokine r...
The respiratory tract pathogen Haemophilus influenzae is responsible for a variety of infections in ...
Background: Viral infection including pandemic influenza may be associated with severe acute respira...
There is considerable evidence that influenza A virus (IAV) promotes adherence, colonization, and su...
International audienceThe complement system is designed to recognise and eliminate invading pathogen...
AbstractThe complement system functions as an immune surveillance system that rapidly responds to in...
To improve COVID-19 therapy, it is essential to understand the mechanisms driving critical illness. ...
The complement cascade defines an important link between the innate and the specific immune system. ...
12 p.- 3 fig.- 2 tab.The surveillance and pathogen fighting functions of the complement system have ...
There is considerable evidence that influenza A virus (IAV) promotes adherence, colonization, and su...