Post-operative complications of penetrating corneal keratoplasty in patients with anterior segment toxic syndrome secondary to cataract surgery

Introduction: Toxic Anterior Segment Syndrome (TASS) after cataract surgery may cause severe corneal decompensation that compromises corneal transparency and may require penetrating corneal keratoplasty to improve visual acuity. Objective: We evaluated the postoperative complications of patients who underwent penetrating corneal transplantation for severe corneal decompensation secondary to TASS after cataract surgery, such as persistent epithelial defect, glaucoma, and primary and secondary transplant button failure. We will also evaluate pre- and postoperative visual acuity, graft survival time, and the presence of anterior chamber disorganization. Methods: Retrospective observational study in which a review of medical records of 9 patients diagnosed with TASS after cataract surgery who underwent penetrating corneal keratoplasty will occur. Results: In the present study all operated patients had glaucoma after penetrating corneal transplantation, and this presence of glaucoma was not correlated with graft survival time and with any other parameter evaluated. The presence of persistent epithelial defect correlated negatively with visual acuity. Conclusion: Postoperative complications of penetrating corneal transplantation in patients with TASS were frequent, such as glaucoma, primary and secondary button failure and persistent epithelial defect. The only complication that compromised visual acuity was the persistent epithelial defect. All patients evolved with glaucoma