none4noSeveral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have emerged, posing a renewed threat to coronavirus disease 2019 containment and to vaccine and drug efficacy. In this study, we analyzed more than 1,000,000 SARS-CoV-2 genomic sequences deposited up to April 27, 2021, on the GISAID public repository, and identified a novel T478K mutation located on the SARS-CoV-2 Spike protein. The mutation is structurally located in the region of interaction with human receptor ACE2 and was detected in 11,435 distinct cases. We show that T478K has appeared and risen in frequency since January 2021, predominantly in Mexico and the United States, but we could also detect it in several European countries.openDi Giacomo S.; ...
The coronavirus disease 2019 (COVID-19) pandemic has affected most countries in the world. Studying ...
Scientists and the public were alarmed at the first large viral variant of SARS-CoV-2 reported in De...
A novel coronavirus (SARS-CoV-2) emerged towards the end of 2019 that caused a severe respiratory di...
SARS-CoV-2 entry in human cells is mediated by the interaction between the viral Spike protein and t...
We aimed to investigate novel emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ...
Emerging mutations and genotypes of the SARS-CoV-2 virus, responsible for the COVID-19 pandemic, hav...
Cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in Manaus, Brazil, r...
Cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in Manaus, Brazil, r...
The emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants in different ...
The comparison of 303,250 human SARS-CoV-2 spike protein sequences with the reference protein sequen...
From PubMed via Jisc Publications RouterHistory: received 2021-08-06, revised 2021-09-23, accepted 2...
Several vaccines with varying efficacies have been developed and are currently administered globally...
Background: Recently, differences in mortality rates of COVID-19 in different geographic areas have ...
Wide-scale SARS-CoV-2 genome sequencing is critical to tracking viral evolution during the ongoing p...
The COVID-19 pandemic, which began in Wuhan (Hubei, China), has been ongoing for about a year and a ...
The coronavirus disease 2019 (COVID-19) pandemic has affected most countries in the world. Studying ...
Scientists and the public were alarmed at the first large viral variant of SARS-CoV-2 reported in De...
A novel coronavirus (SARS-CoV-2) emerged towards the end of 2019 that caused a severe respiratory di...
SARS-CoV-2 entry in human cells is mediated by the interaction between the viral Spike protein and t...
We aimed to investigate novel emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ...
Emerging mutations and genotypes of the SARS-CoV-2 virus, responsible for the COVID-19 pandemic, hav...
Cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in Manaus, Brazil, r...
Cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in Manaus, Brazil, r...
The emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants in different ...
The comparison of 303,250 human SARS-CoV-2 spike protein sequences with the reference protein sequen...
From PubMed via Jisc Publications RouterHistory: received 2021-08-06, revised 2021-09-23, accepted 2...
Several vaccines with varying efficacies have been developed and are currently administered globally...
Background: Recently, differences in mortality rates of COVID-19 in different geographic areas have ...
Wide-scale SARS-CoV-2 genome sequencing is critical to tracking viral evolution during the ongoing p...
The COVID-19 pandemic, which began in Wuhan (Hubei, China), has been ongoing for about a year and a ...
The coronavirus disease 2019 (COVID-19) pandemic has affected most countries in the world. Studying ...
Scientists and the public were alarmed at the first large viral variant of SARS-CoV-2 reported in De...
A novel coronavirus (SARS-CoV-2) emerged towards the end of 2019 that caused a severe respiratory di...