Stabilization of a chemostat model with Haldane growth functions and a delay in the measurements

The stabilization of equilibria in chemostats with measurement delays is a complex and challenging problem, and is of significant ongoing interest in bioengineering and population dynamics. In this paper, we solve an output feedback stabilization problem for chemostat models having two species, one limiting substrate, and either Haldane or Monod growth functions. Our feedback stabilizers depend on a given linear combination of the species concentrations, which are both measured with a constant time delay. The values of the delays are unknown. Instead, one only knows an upper bound on the delays, and we allow the upper bound to be arbitrarily large. The stabilizing feedback depends on the known upper bound for the delays as well. Our work is based on a LyapunovKrasovskii argument. © 2010 Elsevier Ltd. All rights reserved