Objective: To investigate the longitudinal evolution of three blood biomarkers: neurofilament light (NFL), glial fibrillary acidic protein (GFAP) and tau, in out-patients and hospitalized patients with mild traumatic brain injury (mTBI) compared to controls, along with their associations—in patients—with clinical injury characteristics and demographic variables, and ability to discriminate patients with mTBI from controls. Methods: A longitudinal observation study including 207 patients with mTBI, 84 age and sex-matched community controls (CCs) and 52 trauma controls (TCs). Blood samples were collected at 5 timepoints: acute (<24 h), 72 h (24–72 h post-injury), 2 weeks, 3 and 12 months. Injury-related, clinical and demographic variables we...
Past and recent attempts at devising objective biomarkers for traumatic brain injury (TBI) in both b...
Several proteins have proven useful as blood-based biomarkers to assist in evaluation and management...
Objective: Mild traumatic brain injury (mTBI) has been insufficiently researched and its definition ...
Objective: Identification and validation of blood-based biomarkers for the diagnosis and prognosis o...
Mild traumatic brain injury (mTBI) is a significant healthcare burden and its diagnosis remains a ch...
The purpose of this study was to correlate the early levels of glial fibrillary acidic protein (GFAP...
Background: Mild traumatic brain injury (mTBI) is a significant healthcare burden and its diagnosis ...
BACKGROUND: Glial fibrillary acidic protein (GFAP) and ubiquitin C-terminal hydrolase-L1 (UCH-L1) ar...
The purpose of this study was to correlate the early levels of glial fibrillary acidic protein (GFAP...
Objective: To determine whether serum neurofilament light (NfL) correlates with CSF NfL, traumatic b...
OBJECTIVE: To examine whether the brain biomarkers total-tau (T-tau), glial fibrillary acidic protei...
Background: The use of blood biomarkers after mild traumatic brain injury (mTBI) has been widely stu...
Mild traumatic brain injury is a relatively common event in contact sports and there is increasing i...
BACKGROUND: Glial fibrillary acidic protein (GFAP) and ubiquitin C-terminal hydrolase- L1 (UCH-L1) a...
Objective: To determine whether neurofilament light (NfL), glial fibrillary acidic protein (GFAP), t...
Past and recent attempts at devising objective biomarkers for traumatic brain injury (TBI) in both b...
Several proteins have proven useful as blood-based biomarkers to assist in evaluation and management...
Objective: Mild traumatic brain injury (mTBI) has been insufficiently researched and its definition ...
Objective: Identification and validation of blood-based biomarkers for the diagnosis and prognosis o...
Mild traumatic brain injury (mTBI) is a significant healthcare burden and its diagnosis remains a ch...
The purpose of this study was to correlate the early levels of glial fibrillary acidic protein (GFAP...
Background: Mild traumatic brain injury (mTBI) is a significant healthcare burden and its diagnosis ...
BACKGROUND: Glial fibrillary acidic protein (GFAP) and ubiquitin C-terminal hydrolase-L1 (UCH-L1) ar...
The purpose of this study was to correlate the early levels of glial fibrillary acidic protein (GFAP...
Objective: To determine whether serum neurofilament light (NfL) correlates with CSF NfL, traumatic b...
OBJECTIVE: To examine whether the brain biomarkers total-tau (T-tau), glial fibrillary acidic protei...
Background: The use of blood biomarkers after mild traumatic brain injury (mTBI) has been widely stu...
Mild traumatic brain injury is a relatively common event in contact sports and there is increasing i...
BACKGROUND: Glial fibrillary acidic protein (GFAP) and ubiquitin C-terminal hydrolase- L1 (UCH-L1) a...
Objective: To determine whether neurofilament light (NfL), glial fibrillary acidic protein (GFAP), t...
Past and recent attempts at devising objective biomarkers for traumatic brain injury (TBI) in both b...
Several proteins have proven useful as blood-based biomarkers to assist in evaluation and management...
Objective: Mild traumatic brain injury (mTBI) has been insufficiently researched and its definition ...