Background: Nuclear factor erythroid 2-related factor 2 (NRF2) is a transcription factor that is indicated to be an important component in promoting cancer metastasis. Accordingly, the role of the transcription factor has been investigated in diverse types of aggressive cancer. However, a comprehensive identification of NRF2 functions in metastatic breast cancer is rather limited despite being one of the leading causes of death worldwide. Objective: This study aims to identify NRF2 binding sites in 66cl4 murine metastatic breast cancer cell line by chromatin immunoprecipitation sequencing (ChIP-seq) to contribute to the understanding of how NRF2 contributes to aggressive breast cancer development. Results: The genome-scale investigation w...
The NRF2 pathway is frequently activated in various cancer types, yet a comprehensive analysis of it...
Nuclear factor E2-related factor 2 (NRF2), a transcription factor, is a master regulator of an array...
BRCA1 is closely related to the pathogenesis of breast cancer. The activity of BRCA1 promoter is reg...
Despite tremendous progress in the understanding of breast cancer (BC), gaps remain in our knowledge...
NR2F2, a member of nuclear receptor subfamily 2, was shown to be associated with cancer, but its rol...
Nuclear factor erythroid-2 related factor-2 (Nrf2) is an oxidative stress-response transcriptional a...
Objective: Owing to the putative role of Nrf2 in the activation of anti-oxidative genes, the present...
Despite tremendous progress in the understanding of breast cancer (BC), gaps remain in our knowledge...
Despite tremendous progress in the understanding of breast cancer (BC), gaps remain in our knowledge...
Jianguo Sun,1,2 Zhibao Zheng,1 Qi Chen,2 Yin Pan,1 Hongsheng Lu,3 Hui Zhang,3 Yingzhi Yu,3 Yuechu Da...
BACKGROUND: The transcription factor Nrf2 is a key regulator of the cellular antioxidant response, a...
Despite tremendous progress in understanding of ovarian cancer, gaps remain in our knowledge of the ...
BRCA1 is closely related to the pathogenesis of breast cancer. The activity of BRCA1 promoter is reg...
Nuclear factor erythroid 2–related factor 2 (Nrf2) serves as a “main regulator” in response to inter...
NRF2 is a redox-responsive transcription factor that regulates expression of cytoprotective genes vi...
The NRF2 pathway is frequently activated in various cancer types, yet a comprehensive analysis of it...
Nuclear factor E2-related factor 2 (NRF2), a transcription factor, is a master regulator of an array...
BRCA1 is closely related to the pathogenesis of breast cancer. The activity of BRCA1 promoter is reg...
Despite tremendous progress in the understanding of breast cancer (BC), gaps remain in our knowledge...
NR2F2, a member of nuclear receptor subfamily 2, was shown to be associated with cancer, but its rol...
Nuclear factor erythroid-2 related factor-2 (Nrf2) is an oxidative stress-response transcriptional a...
Objective: Owing to the putative role of Nrf2 in the activation of anti-oxidative genes, the present...
Despite tremendous progress in the understanding of breast cancer (BC), gaps remain in our knowledge...
Despite tremendous progress in the understanding of breast cancer (BC), gaps remain in our knowledge...
Jianguo Sun,1,2 Zhibao Zheng,1 Qi Chen,2 Yin Pan,1 Hongsheng Lu,3 Hui Zhang,3 Yingzhi Yu,3 Yuechu Da...
BACKGROUND: The transcription factor Nrf2 is a key regulator of the cellular antioxidant response, a...
Despite tremendous progress in understanding of ovarian cancer, gaps remain in our knowledge of the ...
BRCA1 is closely related to the pathogenesis of breast cancer. The activity of BRCA1 promoter is reg...
Nuclear factor erythroid 2–related factor 2 (Nrf2) serves as a “main regulator” in response to inter...
NRF2 is a redox-responsive transcription factor that regulates expression of cytoprotective genes vi...
The NRF2 pathway is frequently activated in various cancer types, yet a comprehensive analysis of it...
Nuclear factor E2-related factor 2 (NRF2), a transcription factor, is a master regulator of an array...
BRCA1 is closely related to the pathogenesis of breast cancer. The activity of BRCA1 promoter is reg...