Dissolvable microneedles and nanofiber dressings to eradicate biofilms and improve wound care

Biofilms are communities of microorganisms consisting of one or more bacterial species that attach to a biotic or abiotic surface. Biofilms are highly common in chronic wounds. To improve wound care treatment, a Janus-type antimicrobial dressing was created to eradicate biofilms in chronic wounds. The dressing consists of two layers: a top layer of electrospun nanofibers and a bottom layer of dissolvable microneedles. The dressings were tested on an ex vivo and in vivo model.https://digitalcommons.unmc.edu/surp2021/1055/thumbnail.jp