A clinical study to evaluate the effect of Shreekhandasava in Madatyaya w.s.r. to Alcohol use disorder

Objective: To study Madatyaya / Alcohol use disorder conceptually and to evaluate the therapeutic effect of Shrikhandasava in Madatyaya/Alcohol use disorder. Design of the study: An open labelled clinical study with pre and post-test design. Source of data: 20 patients diagnosed as Madatyaya fulfilling the diagnostic and inclusion criteria were selected from IPD and OPD of Shri Dharmasthala Manjunatheshwara Ayurveda Hospital, Kutpadi, Udupi. Intervention: Shreekhandasava in a dose of 24ml, twice a day after food for 14 days. Main outcome measures: Percentage changes in symptoms including CIWA-Ar score. Results: the statistical analysis was done by paired ‘t’ test and results obtained were highly significant ( p<0.001). Overall improvement of patients, 10% got complete remission, 85% got marked improvement and 5% got moderate improvement from the symptoms. Conclusion: Test drug (Shrikhandasava) shows significant results in remission of signs and symptoms of Madatyaya