Physico-chemical characterization of Rasagarbha Pottali - An Approach to Standardization

In Rasashastra among the four Kalpa’s, Pottali Rasakalpas have unique place in Ayurvedic therapeutics because of their qualities, very compact in structure and quick acting due to its high potency. Here a research work is carried out on Rasagarbha Pottali by molten sulphur method for about 6hrs Paka and analysed with classical and modern parameters. Similarly, an attempt was also made to differentiate the structure of the drug before Paka (RGPK) and after Paka (RGP). Where particle size found to be in RGP is 475.3nm. In SEM-EDAX there is presence of C, Au, Hg, S and Si. XRD showed HgS and Au2S compounds with cubic in structure. FTIR proved that it has Organic Compounds with functional groups like Alkyl halides, Aromatics, Alkenes, Amines. Along with these other physico-chemical tests, NPST were carried out to show the standard values of final product. Overall, a remarkable difference was observed in the samples RGPK and RGP