Validity of Qsofa, news and rems express-scales in patients with COVID-19 (Virus not identified): A retrospective observational study

Objective. To compare the informative value of the Quick Sequential scales (Sepsis-Related Organ Failure Assessment, qSOFA), National Early Warning Score (NEWS) and Rapid Emergency Medicine Score (REMS) in patients with COVID-19 (no virus iden-tified) admitted to ICU. Material and methods. A single-center retrospective observational study included 100 medical records of patients hospitalized to the Regional Clinical Hospital 2 in April — July 2020. Mean age of patients was 73.2 (range 37.0—94.0) years. ROC analysis of the qSOFA, NEWS and REMS scales regarding prediction of mortality was performed. Results. AUC for the NEWS scale (0.887 [95% CI 0.805—0.942]) was significantly higher compared to the qSOFA (0.802 [95% CI 0.708—0.877]) and REMS scales (0.836 [95% CI 0.746—0.904]) in prediction of mortality in patients with COVID-19 (no virus identified). There were significant differences between AUC for the NEWS and qSOFA scales (p=0.0032), while these values were similar for NEWS and REMS (p=0.2117), REMS and qSOFA (p=0.4669). Conclusion. NEWS, qSOFA and REMS scales showed good calibration and resolution. The NEWS scale has a high statistical accuracy for resolution data, qSOFA — for calibration data