Gastrointestinal Stromal Cell Tumor (GIST) Presenting as an Abdomino-pelvic Tumor

Background: Gastrointestinal stromal tumors (GIST) are rare mesenchymal tumors that may mimic ovarian tumor on presurgical testing. These tumors are usually asymptomatic, often discovered accidentally during endoscopic or radiologic examinations,. Case Presentations: In first case a 50 years old woman presented with irregular bleeding per vaginum, intermittent right lower abdominal pain and urinary frequency over the preceding 4 months. Physical examination and imaging studies revealed a pelvic mass of 18-week-gestational size. An exploratory laparotomy showed a huge fragile pelvic tumor, measuring 20 × 20 cm, arising from the jejunum. Immunohistochemical staining confirmed the presence of CD-117. In second case an 53-year-old, postmenopausal, woman presented with abdominal fullness and constipation for the preceding 3-4 days. Physical examination and imaging studies revealed a huge pelvic mass, suggestive of a cystic degenerated myoma. An exploratory laparotomy revealed a large tumor originating from the ileum. Conclusion: Gynecologists should keep in mind the possibility of non gynaecological tumors (GISTs) in the differential diagnosis in pelvic tumors