The hydrolytic degradation of irbesartan in borate buffer (pH 9.80) at 70 ± 1° C was studied. The degradation was hydroxide ion catalyzed. The separation of irbesartan from the degraded product was achieved by high performance liquid chromatography. The isolated degraded product was confirmed by its retention time. The characterization was done by elemental and infrared spectroscopic analyses. The characterized degraded product is methyl-biphenyltetrazole.Keywords: hydrolysis, degradation, irbesartan, aqueous solution, bufferNigerian Journal of Pharmaceutical Research, Vol. 8 No 1 pp. 43 - 45 (September 2010
A simple, sensitive and accurate HPLC method with high throughput has been developed and validated f...
A simple, accurate and precise spectroscopic method was developed for simultaneous estimation of Irb...
Objective: Irbesartan is an antihypertensive with limited bioavailability. The objective of the stud...
A simple, specific, accurate and precise new high performance liquid chromatographic method was deve...
Objective: To develop and validate a simple, specific, accurate, precise and sensitive reverse phase...
Objective: The mass characterization of five trace level related impurities of Irbesartan was perfor...
AbstractWith the objective of reducing analysis time and maintaining good efficiency, there has been...
Simple, sensitive, accurate, precise and rapid ultraviolet (UV) spectrophotometric method was develo...
ABSTRACT Spectrophotometric method was developed for estimation of Irbesartan ( IRB ) in pure for...
A simple, rapid, precise, rapid, sensitive and reproducible reverse phase high performance liquid ch...
AbstractA simple, sensitive, precise high-performance thin-layer chromatographic (HPTLC) method has ...
artikel salman :Preparation and Physicochemical Characterization of Solid Dispersion of Irbesartan w...
Recently, many studies highlighted the consistent finding of irbesartan in effluents from wastewater...
Irbesartan (IRB) is one of the drugs used for the treatment of hypertension. The present work develo...
AIM: The aim of the present study was to prepare and characterize the solid dispersion of poorly sol...
A simple, sensitive and accurate HPLC method with high throughput has been developed and validated f...
A simple, accurate and precise spectroscopic method was developed for simultaneous estimation of Irb...
Objective: Irbesartan is an antihypertensive with limited bioavailability. The objective of the stud...
A simple, specific, accurate and precise new high performance liquid chromatographic method was deve...
Objective: To develop and validate a simple, specific, accurate, precise and sensitive reverse phase...
Objective: The mass characterization of five trace level related impurities of Irbesartan was perfor...
AbstractWith the objective of reducing analysis time and maintaining good efficiency, there has been...
Simple, sensitive, accurate, precise and rapid ultraviolet (UV) spectrophotometric method was develo...
ABSTRACT Spectrophotometric method was developed for estimation of Irbesartan ( IRB ) in pure for...
A simple, rapid, precise, rapid, sensitive and reproducible reverse phase high performance liquid ch...
AbstractA simple, sensitive, precise high-performance thin-layer chromatographic (HPTLC) method has ...
artikel salman :Preparation and Physicochemical Characterization of Solid Dispersion of Irbesartan w...
Recently, many studies highlighted the consistent finding of irbesartan in effluents from wastewater...
Irbesartan (IRB) is one of the drugs used for the treatment of hypertension. The present work develo...
AIM: The aim of the present study was to prepare and characterize the solid dispersion of poorly sol...
A simple, sensitive and accurate HPLC method with high throughput has been developed and validated f...
A simple, accurate and precise spectroscopic method was developed for simultaneous estimation of Irb...
Objective: Irbesartan is an antihypertensive with limited bioavailability. The objective of the stud...