The possible value of

Prosopis africana, Family Leguminoceae, is used in ethnomedicine to treat different ailments including, malaria in Nigeria, male sterility in Sudan and as a cardiotonic agent in Senegal. This research aims at evaluating the antituberculosis activity, analgesic and anti-inflammatory action of the stem bark extract of P. africana. Preliminary studies using the agar dilution method show that the stem bark extract of Prosopis africana (1000, 1500, 2000 ìg/ml) hasinhibitory activity against clinical isolates of Mycobacterium tuberculosis, the causative organism of tuberculosis (TB). It also significantly inhibited B. subtilis and S. aureus but not the gram-negative organisms: E. coli, P. aeruginosa, S. typhii and yeast (C. albicans) at all test concentrations (1000, 2000, 3000 ìg/ml). Aqueous extracts of Prosopis (100 and 200 mg/kg i.p) significantly inhibited acetic acid induced writhing in mice and a dose and timedependentinhibition of the egg white induced paw oedema (