Glycaemic variations after administration of Irvingia gabonensis

The action of Irvingia gabonensis seed fractions in reducing or slowing down the intestinal absorption of glucose was evaluated in normoglycaemic rats. The crude seeds (CS), the defatted seeds (DS) and the protein fraction (PF) were administered at dose of 400mg/ kg body weight to normoglycemic rats submitted to oral glucose test (OGTT) with glucose (2g/kg body weight). The results obtained show a significant reduction of the postprandial glucose level after a glucose load of (2g/kg body weight) as well as fasting blood glucose levels with the three fractions. Keywords: antihyperglycaemic, blood glucose, solubles fibres, Irvingia seeds fractions African Journal of Traditional, Complementary and Alternative Medicines Vol. 3(4) 2006: 94-10