The reaction of chloroheterocycles with some isoxazolones under microwave irradiation and under solvent-free conditions to give the corresponding mono isoxazolinyl derivatives is reported. The main advantages of this method are: (i) elimination of the nitrogen gas (N2), (ii) solvent-free conditions, (iii) microwave irradiation, (iv) avoiding the use of silica gel for purification of the products, and (v) higher and shorter reaction times. These compounds have potential applications as DNA intercalators.Keywords: Isoxazolones, N-aryl isoxazolones, solvent-free, 2-chlorobenzoxazole, 2-chlorobenzothiazol
AbstractIn this paper, we have described the conventional and microwave methods for the synthesis of...
Twelve novel 5-trichloromethyl-4,5-dihydro-1H-1-pyrazole ethyl esters have been synthesized in good ...
Objective: A facile and efficient synthesis of new pyrazoloisoxazole, isoxazolopyridine and isoxazol...
The synthesis of series of 3-aryl-4-dihydrooxazolyl-5-methyl trisubstituted isoxazoles (VI) is repor...
1,2,4-Triazole-3-one (3), acquired from cinnamaldehyde was converted to the corresponding carbox(thi...
An efficient, catalyst free, 1,3-dipolar cycloaddition strategy to conjugate nucleosides and nucleot...
459-464A series of 3-methyl-4-((3-aryl-1-phenyl-1H-pyrazol-4-yl)methylene)isoxazol-5(4H)-one derivat...
Benzo[a]phenoxazinium salts are usually synthesised by condensation reaction of nitrosoanilines or n...
A novel catalyst-free synthetic approach to 1,2,3-triazolobenzodiazepinones has been developed and o...
The synthesis of N-protected 5-oxazolidinones using amino acids, paraformaldehyde and p-toluene sulf...
1784-1786Trimolecular condensation of N-(5-methyl-3- isoxazolyl)- N'-aryl ureas 2 with aqueous for...
The synthesis of N-protected 5-oxazolidinones using amino acids, paraformaldehyde and p-toluene sulf...
627-633A series of compounds namely 6-{4'-[(4''-methylpiperazinyl)diazenyl]phenyl} -4-(substituted...
Novel isoxazoline and pyrazoline derivatives of N-substituted saccharin were synthesized in good yie...
Organic Chemistry Laboratory, Sikkim Government College, Gangtok-737 I 02, Sikkim, India E-mail : b...
AbstractIn this paper, we have described the conventional and microwave methods for the synthesis of...
Twelve novel 5-trichloromethyl-4,5-dihydro-1H-1-pyrazole ethyl esters have been synthesized in good ...
Objective: A facile and efficient synthesis of new pyrazoloisoxazole, isoxazolopyridine and isoxazol...
The synthesis of series of 3-aryl-4-dihydrooxazolyl-5-methyl trisubstituted isoxazoles (VI) is repor...
1,2,4-Triazole-3-one (3), acquired from cinnamaldehyde was converted to the corresponding carbox(thi...
An efficient, catalyst free, 1,3-dipolar cycloaddition strategy to conjugate nucleosides and nucleot...
459-464A series of 3-methyl-4-((3-aryl-1-phenyl-1H-pyrazol-4-yl)methylene)isoxazol-5(4H)-one derivat...
Benzo[a]phenoxazinium salts are usually synthesised by condensation reaction of nitrosoanilines or n...
A novel catalyst-free synthetic approach to 1,2,3-triazolobenzodiazepinones has been developed and o...
The synthesis of N-protected 5-oxazolidinones using amino acids, paraformaldehyde and p-toluene sulf...
1784-1786Trimolecular condensation of N-(5-methyl-3- isoxazolyl)- N'-aryl ureas 2 with aqueous for...
The synthesis of N-protected 5-oxazolidinones using amino acids, paraformaldehyde and p-toluene sulf...
627-633A series of compounds namely 6-{4'-[(4''-methylpiperazinyl)diazenyl]phenyl} -4-(substituted...
Novel isoxazoline and pyrazoline derivatives of N-substituted saccharin were synthesized in good yie...
Organic Chemistry Laboratory, Sikkim Government College, Gangtok-737 I 02, Sikkim, India E-mail : b...
AbstractIn this paper, we have described the conventional and microwave methods for the synthesis of...
Twelve novel 5-trichloromethyl-4,5-dihydro-1H-1-pyrazole ethyl esters have been synthesized in good ...
Objective: A facile and efficient synthesis of new pyrazoloisoxazole, isoxazolopyridine and isoxazol...