Electrocatalytic Activity of Electropolymerized Cobalt Tetraaminophthalocyanine Film Modified Electrode towards 6-Mercaptopurine and 2-Mercaptobenzimidazole

The electrocatalytic activity of electropolymerized cobalt tetraaminophthalocyanine (poly-CoTAPc) film modified on the glassy carbon electrode (GCE) towards 6-mercaptopurine (6MP) and 2-Mercaptobenzimidazole (MBI) was studied. Comparing with the case at the unmodified GCE, the poly-CoTAPc film decreased the overpotential of oxidation of 6MP (1.0 × 10–3 mol L–1) and MBI (1.0×10–3 mol L–1) by 335 and 189mV, respectively, and increased the peak current by about 3 and 2 times, respectively, while the reduction potential of the disulphide product of previous oxidation of 6MP shifted positively by 312 mV and the peak current increased by 40 times in 0.1 mol L–1 phosphate buffer solution (PBS, pH = 2.0). The poly-CoTAPc film exhibited efficiently electrocatalytic activity for 6MP and MBI with relatively high sensitivity, stability and long-life.Keywords: Electrocatalysis, 6-mercaptopurine, 2-mercaptobenzimidazole, Cobalt Tetraaminophthalocyanine, Electropolymeric Fil