Purpose: To synthesize and characterize novel thiazolidinone derivatives and screen them for antitubercular activity. Methods: A series of twelve novel thiazolidinones 4a-l have been synthesized by cyclocondensation of various Schiff bases of amino thiadiazole with thioglycollic acid. Various Schiff bases 3a-l were synthesized by condensation of 2-amino-5-aryl-5H-thiazolo[4,3-b]-l,3,4-thiadiazole with various aryl aldehydes. The synthesized compounds were characterized by FTIR, 1H-NMR, 13C-NMR and mass spectrometry. Docking studies were carried out for the synthesized compounds which were also evaluated for in vitro anti-tubercular activity at a concentration of 0.1 – 100.0 μg/mL by Microplate Blue Alamar Assay method. Pyrazinami...
Department of Chemistry, Bhavnagar University, Bhavnagar-364 002 Manuscript received 17 May 1983, a...
AbstractA novel series of Schiff bases 4a–n was prepared from 2-hydrazinyl-N-(2-(1-hydroxycyclohexyl...
Thiazolidinones and their derivatives are an important class of compounds in organic and medicinal c...
Purpose: To synthesize and characterize novel thiazolidinone derivatives and screen them for antitub...
Department of Pharmaceutical Chemistry, The Oxford College of Pharmacy, Bangalore-560 068, India E-...
A series of new Schiff bases were synthesized through the condensation reaction of 1,3,4-thiadiazole...
A series of new Schiff bases were synthesized through the condensation reaction of 1,3,4-thiadiazole...
Objective: The objective of the paper was to synthesize and characterize new derivatives of thiazole...
To develop novel antimycobacterial agents, a new series of thiazolidinone-azole hybrids 4a-b, 5a-b a...
Chemistry Department. B. K. M. Science College. Valsad-396 001 Manuscript received 30 May 1991. rev...
The 6-(4-substituted aryl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)imidazo[2,1-b][1,3,4]thiadiazole (2a-f) w...
4-thiazolidinones are among t h e most extensively investigated class of organic compounds. Thiazoli...
A novel series of Schiff bases 4a–n was prepared from 2-hydrazinyl-N-(2-(1-hydroxycyclohexyl)-2-(4-m...
AbstractNew series of N-[2-{2-(substitutedphenyl)-4-oxo-5-(substitutedbenzylidene)-1,3-thiazolidine}...
BACKGROUND Thiazole and benzothiazole derivatives, as well as thiazolidinones are very important sca...
Department of Chemistry, Bhavnagar University, Bhavnagar-364 002 Manuscript received 17 May 1983, a...
AbstractA novel series of Schiff bases 4a–n was prepared from 2-hydrazinyl-N-(2-(1-hydroxycyclohexyl...
Thiazolidinones and their derivatives are an important class of compounds in organic and medicinal c...
Purpose: To synthesize and characterize novel thiazolidinone derivatives and screen them for antitub...
Department of Pharmaceutical Chemistry, The Oxford College of Pharmacy, Bangalore-560 068, India E-...
A series of new Schiff bases were synthesized through the condensation reaction of 1,3,4-thiadiazole...
A series of new Schiff bases were synthesized through the condensation reaction of 1,3,4-thiadiazole...
Objective: The objective of the paper was to synthesize and characterize new derivatives of thiazole...
To develop novel antimycobacterial agents, a new series of thiazolidinone-azole hybrids 4a-b, 5a-b a...
Chemistry Department. B. K. M. Science College. Valsad-396 001 Manuscript received 30 May 1991. rev...
The 6-(4-substituted aryl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)imidazo[2,1-b][1,3,4]thiadiazole (2a-f) w...
4-thiazolidinones are among t h e most extensively investigated class of organic compounds. Thiazoli...
A novel series of Schiff bases 4a–n was prepared from 2-hydrazinyl-N-(2-(1-hydroxycyclohexyl)-2-(4-m...
AbstractNew series of N-[2-{2-(substitutedphenyl)-4-oxo-5-(substitutedbenzylidene)-1,3-thiazolidine}...
BACKGROUND Thiazole and benzothiazole derivatives, as well as thiazolidinones are very important sca...
Department of Chemistry, Bhavnagar University, Bhavnagar-364 002 Manuscript received 17 May 1983, a...
AbstractA novel series of Schiff bases 4a–n was prepared from 2-hydrazinyl-N-(2-(1-hydroxycyclohexyl...
Thiazolidinones and their derivatives are an important class of compounds in organic and medicinal c...