Effect of Aloe Barbadensis on Rat's Uterine Contractility

The present study was undertaken to investigate the effect of the aqueous extract of Aloe barbadensis on the contractility of the uterine stip of a rat. Aqueous extract at final bath concentrations (FBC)1x10-4 mg/ml to 3x101 mg/ml produced a progressive increase in frequency of contraction of the uterine strip. The force of contraction of the uterine strip decreased gradually from FBC of 1x10-4mg/ml to 3x10-3mg/ml. However at higher FBC, Aloe bardadensis showed a progressive increase in force of contraction. We therefore suggest that Aloe barbadensis has some abortifacient effects at high does. KEY WORDS: Aloe barbadensis, Uterine contraction, Purgative. Nigerian Journal of Health and Biomedical Sciences Vol.3(2) 2004: 120-12