Vibrio Cholerae 01 Infections In Jos, Nigeria

A study to determine the prevalence of Vibrio cholerae 01 in stool sample submitted for routine examination of enteric pathogens, as well as identify the serotypes and antibiogram of the isolates to commonly used antibiotics was undertaken. The survey involved the examination of 774 (763 stool and 11 rectal swabs) specimens obtained from different patients seen at the Jos University Teaching Hospital (JUTH). Of the total number examined, 34 (4.39%) yielded Vibrio cholerae 01. All of them were Inaba serotype of El-Tor biotype. The age group 20-29 years had the highest rate, 21 (6.95%). Rectal swabs yielded a higher number of isolates, 9 (81.82%) from 11 specimens compared to 25 (3.28%) from 763 stool specimens. The organism is most prevalent during the mid-rainy season (June/July) since most of the isolates 29 (85.29%) of the 34 isolates were isolated during this period (P < 0.05). Isolates were very sensitive to ofloxacin, erythromycin and tetracycline but resistant to chloramphenicol, ampicillin, cloxacillin and penicillin G. This study demonstrates that Vibrio cholerae 01 is endemic in our environment. Afr. J. Clin. Exper. Microbiol. 2004; 5 (3): 260-26