Colonic epithelial cathelicidin (LL-37) expression intensity is associated with progression of colorectal cancer and presence of CD8+ T cell infiltrate

Porter, Ross John
Murray, Graeme
Alnabulsi, Abdo
Humphries, Matthew P
James, Jacqueline A
Salto-Tellez, Manuel
Craig, Stephanie G.
Wang, Ji Ming
Yoshimura, Teizo
McLean, Mairi

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Publication date

September 2021

DOI

10.1002/cjp2.222

Publisher

Wiley

Journal

The Journal of Pathology Clinical Research

Language

English

Abstract

ACKNOWLEDGEMENTS: We wish to acknowledge the Grampian Tissue Biorepository for assistance in tissue preparation and immunohistochemistry, and also Daniel Brice and Susan Berry for their help with the organoid model. This study was funded in part by The Carnegie Trust for the Universities of Scotland and British Society for Immunology (studentship awards to RJP within the MHM laboratory).Peer reviewedPublisher PD

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Colonic epithelial cathelicidin (LL-37) expression intensity is associated with progression of colorectal cancer and presence of CD8+ T cell infiltrate

Abstract

Extracted data

Colonic epithelial cathelicidin (LL-37) expression intensity is associated with progression of colorectal cancer and presence of CD8+ T cell infiltrate

Abstract

Extracted data

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