Detect Incidence of Prostate Carcinoma in TURP Chips Specimens and its Histopathological Diagnosis- A Retrospective Study, Andhra Pradesh

Background:Benign prostatic hyperplasia is common condition in men over 50 years of age and shows remarkable racial and geographical variations in incidence and mortality. Inflammation, hyperplastic changes of prostate, and tumors are the commonest pathological processes that affect prostate gland. Aim of the study: To detectincidence of prostate carcinoma in Transurethral resection of the prostate (TURP) chips specimens and its histopathological diagnosis.Methods:This retrospective study done for duration of one year from January 2019 to December 2019. The TURP specimens were studied for histopathology.Results:In 45 cases of Benign prostatic hyperplasia (BPH) was most common diagnosis reported ie, about 60 % (27/45). BPH with chronic prostatitis was seen in 22.2 % (10/45) cases. Carcinoma prostate was seen in 20 % (09/45) cases. Out of these 04 belonged to T1a (25.8 %) and 05 belonged to T1b (74.2 %).Conclusions:Prostatic enlargement is common with increasing age and most often it is due to benign prostatic hyperplasia. In the present study, incidence of carcinoma prostate was 20 %. Gleason score 7 is the most common score encountered in prostatic adenocarcinoma. Prostatic carcinoma can often have serum PSA levels in the grey zone of 4 to 10 ng/ml