The North Natal Valley (NNV) and the Mozambique Coastal Plain (MCP) are key areas for the understanding of the SW Indian Ocean history since the Gondwana break‐up. Nevertheless, the deep structures and the nature of the NNV and MCP remain discussed in the absence of deep geophysical data. In 2016, the NNV, MCP and Limpopo margin (LM) have been investigated along 7 wide‐angle and MCS profiles. The combined wide‐angle and reflection seismic interpretation along the N‐S MZ7 profile reveals an upper sedimentary sequence characterized by low velocities generally not exceeding 3 km/s, with thicknesses varying from 0.150 km in the central part to ∼2.8 km in the south. The underlying sequence is formed of a 2.5‐3.0 km thick volcano‐sedimentary sequ...