Cytotoxicity, antimicrobial and antioxidant activity of Daucus carota L., Lycopersicon esculentum Mill. and Capsicum annuum L.

The objective of this study was to evaluate the cytotoxicity, antimicrobial and antioxidant activities of extracts of Daucus carota L., Lycopersicon esculentum Mill. and Capsicum annuum L. grown in Central Serbia. The content of phenolic compounds in the extracts was determined using spectrophotometric and HPLC analysis. These plant extracts proved to be potent inhibitors of cell growth in the cell lines (FemX and LS 174). The IC50 values against FemX and LS174 cell lines were 33.52 +/- 1.08 and 40.22 +/- 0.03 mu g/mL, respectively. The highest antioxidant capacity was found in C. annuum L. (98.01 +/- 0.72 mu g AA/g) and D. carota L. (48.51 +/- 1.18 mu g AA/g) extracts. The test extracts showed strong to moderate antimicrobial activity (19.53 - 312.50 mu g/mL). D. carota L., L. esculentum Mill. and C. annuum L. extracts can serve as new dietary and food supplements