Add to ORKGObjective: The objective of the study was to investigate the inhibitory activity of polyisoprenoids from Nypa fruticans leaves on the expression of cyclooxygenase 2 (COX-2) against colon cancer cells.Methods: Anticancer activity performed was tested by dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide method on colon cancer cell WiDr. The expression of COX-2 was observed by the immunocytochemistry method.Result: Polyisoprenoids from N. fruticans leaves exhibit anticancer activity on WiDr cells through inhibition of COX-2 expression with IC50 180.186±7.16 μg/ml.Conclusions: This study showed that polyisoprenoids from N. fruticans leaves promise chemopreventive agents for colon cancer through COX-2 inhibition
Objective: To evaluate the potential role of the polysaccharides of the marine algae as an anticance...
Objective: The current investigation focuses on the study of efficacy of whole plant of Polycarpaea ...
In inflammatory events, the cyclooxygenase-2 enzyme (COX-2) catalyses prostaglandin biosynthesis. Th...
AbstractObjectiveTo determine the inhibition activity of Typhonium flagelliforme Lodd. Blume (T. fla...
The mangrove plant is known to produce secondary metabolite compounds, mainly isoprenoids. Polyisopr...
Objective: The incidence of colorectal cancer has been growing faster than most other cancers in the...
BACKGROUND: According to the Global Cancer Observatory in 2018, Asia was the first to note the incid...
 Objective: The aim of this study was to evaluate the colon cancer protective activity of Cycas rev...
Objective: The objective of this project is to evaluate the chemoprevention efficacy of locally bioa...
BACKGROUND: Mangroves secondary metabolites are mostly consisting of sterols, ubiquinones, isoprenoi...
Ugnė Čeponytė, Miglė Paškevičiū tė, Vilma Petrikaitė Department of Drug Chemistry, Faculty o...
Colon cancer, the leading cause of global cancer-related mortality, demands innovative therapeutic a...
Objective: This study aims to isolate the active anticancer compound from ethyl acetate fraction ext...
Objective: The effectiveness of the selective COX-2 inhibitors in colorectal cancer chemoprevention ...
Objective: To determine the inhibition activity of Typhonium flagelliforme Lodd. Blume (T. flagellif...
Objective: To evaluate the potential role of the polysaccharides of the marine algae as an anticance...
Objective: The current investigation focuses on the study of efficacy of whole plant of Polycarpaea ...
In inflammatory events, the cyclooxygenase-2 enzyme (COX-2) catalyses prostaglandin biosynthesis. Th...
AbstractObjectiveTo determine the inhibition activity of Typhonium flagelliforme Lodd. Blume (T. fla...
The mangrove plant is known to produce secondary metabolite compounds, mainly isoprenoids. Polyisopr...
Objective: The incidence of colorectal cancer has been growing faster than most other cancers in the...
BACKGROUND: According to the Global Cancer Observatory in 2018, Asia was the first to note the incid...
 Objective: The aim of this study was to evaluate the colon cancer protective activity of Cycas rev...
Objective: The objective of this project is to evaluate the chemoprevention efficacy of locally bioa...
BACKGROUND: Mangroves secondary metabolites are mostly consisting of sterols, ubiquinones, isoprenoi...
Ugnė Čeponytė, Miglė Paškevičiū tė, Vilma Petrikaitė Department of Drug Chemistry, Faculty o...
Colon cancer, the leading cause of global cancer-related mortality, demands innovative therapeutic a...
Objective: This study aims to isolate the active anticancer compound from ethyl acetate fraction ext...
Objective: The effectiveness of the selective COX-2 inhibitors in colorectal cancer chemoprevention ...
Objective: To determine the inhibition activity of Typhonium flagelliforme Lodd. Blume (T. flagellif...
Objective: To evaluate the potential role of the polysaccharides of the marine algae as an anticance...
Objective: The current investigation focuses on the study of efficacy of whole plant of Polycarpaea ...
In inflammatory events, the cyclooxygenase-2 enzyme (COX-2) catalyses prostaglandin biosynthesis. Th...