THROMBOLYTIC ACTIVITY OF C.AMADA AND C.CAESIA

Objective: To compare the thrombolytic activity of C.amada and C. caesia.Methods: Hydro alcoholic extractions of C.amada and C. caesia were prepared. Clot lysis potential of the extracts was checked and the results were statistically analysed.Result and Conclusion: On comparing the thrombolytic potential, the % of clot lysis of silver nanoparticle synthesized using C. caesia (51%) was found to be higher than C.amada (34.7%) extract. Similarly C. caesia extract (38.75 ± 2.217) showed higher % of clot lysis than C.amada (34.74 ± 6.074). The mean percentage of clot lysis of rhizome extracts and synthesized silver nanoparticle were statistically more significant (p value < 0.05) when compared to the positive control streptokinase and negative control water. Active component involvement analysis will be helpful to utilize the C.amada and C. caesia as potent therapeutic agent.Key words: C.amada, C. caesia, thrombolytic potential