Population pharmacokinetics (PPK) is the study of this variability, its source and magnitude in populations. This information is used to design dosage regimens that account for individual patient characteristics. Objective: The objective of this study was to perform a Non linear mixed-effects analysis of the pharmacokinetics of metoprolol, indicated for treating hypertension and to study the effect of covariates like age, body surface area [BSA] and creatinine clearance [CRCL] on the population pharmacokinetics of metoprolol in South Indian hypertensive patients.  Methods: A simple, rapid and sensitive isocratic HPLC-UV method for detection and quantification of metoprolol in plasma had been developed. Intra-and inter-assay var...
Purpose: To develop a sensitive, simple and validated high performance liquid chromatography (HPLC) ...
Background Metoprolol is the one of the most commonly used β-blockers in the treatment of ischemic h...
Metoprolol, a beta-1 selective adrenegic receptor blocker antihypertensive agent is fairly new in Ni...
The evolution in the development of drugs has increased the popularity of physiologically based phar...
Introduction: Population pharmacokinetics (PPK) is the study of this variability, its source and mag...
The evolution in the development of drugs has increased the popularity of physiologically based phar...
Objective: The current project was undertaken to develop and validate a simple method for estimation...
Introduction: This article seeks to clarify if gender-based differences occur in the pharmacokinetic...
A simple, specific, sensitive and rapid Reverse phase high performance liquid chromatographic (RP-HP...
Premenopausal women may be most vulnerable to acute coronary syndromes at a point in their menstrual...
A simple, specific, sensitive and rapid Reverse phase high performance liquid chromatographic (RP-HP...
Aims: The aims of this study were to study the efficacy and tolerability of felodipine extended rele...
A simple, specific, sensitive and rapid Reverse phase high performance liquid chromatographic (RP-HP...
Aims: The aims of this study were to study the efficacy and tolerability of felodipine extended rele...
Aims: The aims of this study were to study the efficacy and tolerability of felodipine extended rele...
Purpose: To develop a sensitive, simple and validated high performance liquid chromatography (HPLC) ...
Background Metoprolol is the one of the most commonly used β-blockers in the treatment of ischemic h...
Metoprolol, a beta-1 selective adrenegic receptor blocker antihypertensive agent is fairly new in Ni...
The evolution in the development of drugs has increased the popularity of physiologically based phar...
Introduction: Population pharmacokinetics (PPK) is the study of this variability, its source and mag...
The evolution in the development of drugs has increased the popularity of physiologically based phar...
Objective: The current project was undertaken to develop and validate a simple method for estimation...
Introduction: This article seeks to clarify if gender-based differences occur in the pharmacokinetic...
A simple, specific, sensitive and rapid Reverse phase high performance liquid chromatographic (RP-HP...
Premenopausal women may be most vulnerable to acute coronary syndromes at a point in their menstrual...
A simple, specific, sensitive and rapid Reverse phase high performance liquid chromatographic (RP-HP...
Aims: The aims of this study were to study the efficacy and tolerability of felodipine extended rele...
A simple, specific, sensitive and rapid Reverse phase high performance liquid chromatographic (RP-HP...
Aims: The aims of this study were to study the efficacy and tolerability of felodipine extended rele...
Aims: The aims of this study were to study the efficacy and tolerability of felodipine extended rele...
Purpose: To develop a sensitive, simple and validated high performance liquid chromatography (HPLC) ...
Background Metoprolol is the one of the most commonly used β-blockers in the treatment of ischemic h...
Metoprolol, a beta-1 selective adrenegic receptor blocker antihypertensive agent is fairly new in Ni...