Growth hormone (GH) deficiency is associated with cognitive decline which occur both in normal aging and in endocrine disorders. Several brain areas express receptors for GH although their functional role is unclear. To determine how GH affects the capacity for learning and memory by specific actions in one of the key areas, the hippocampus, we injected recombinant adeno-associated viruses (rAAVs) in male rats to express green fluorescent protein (GFP) combined with either GH, antagonizing GH (aGH), or no hormone, in the dorsal CA1. We found that aGH disrupted memory in the Morris water maze task, and that aGH treated animals needed more training to relearn a novel goal location. In a one-trial spontaneous location recognition test, the GH ...
Contributions of somatotropic hormonal activity to memory functions in humans, which are suggested b...
Cognitive impairment is common after stroke, and disturbances in hippocampal function are often invo...
Cataloged from PDF version of article.Alterations in the alpha-amino-3-hydroxy-5-methyl-4-isoxazolep...
Growth hormone (GH) deficiency is associated with cognitive decline which occur both in normal aging...
Growth hormone (GH) deficiency is associated with impaired learning and memory. One possible target ...
Alterations in the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor (AMPA-R) and N-meth...
The hippocampus is remarkably plastic and has the ability to modify its processes throughput the lif...
Growth hormone (GH) deficiency is associated with impaired learning and memory. One possible target ...
Cognitive impairments are an increasing health problem worldwide. In the developed countries, the av...
Cognitive impairments are an increasing health problem worldwide. In the developed countries, the av...
Cognitive impairments are an increasing health problem worldwide. In the developed countries, the av...
Cognitive impairment is common after stroke, and disturbances in hippocampal function are often invo...
The hippocampus is remarkably plastic and has the ability to modify its processes throughput the lif...
The interest for the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis and its role in the...
The interest for the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis and its role in the...
Contributions of somatotropic hormonal activity to memory functions in humans, which are suggested b...
Cognitive impairment is common after stroke, and disturbances in hippocampal function are often invo...
Cataloged from PDF version of article.Alterations in the alpha-amino-3-hydroxy-5-methyl-4-isoxazolep...
Growth hormone (GH) deficiency is associated with cognitive decline which occur both in normal aging...
Growth hormone (GH) deficiency is associated with impaired learning and memory. One possible target ...
Alterations in the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor (AMPA-R) and N-meth...
The hippocampus is remarkably plastic and has the ability to modify its processes throughput the lif...
Growth hormone (GH) deficiency is associated with impaired learning and memory. One possible target ...
Cognitive impairments are an increasing health problem worldwide. In the developed countries, the av...
Cognitive impairments are an increasing health problem worldwide. In the developed countries, the av...
Cognitive impairments are an increasing health problem worldwide. In the developed countries, the av...
Cognitive impairment is common after stroke, and disturbances in hippocampal function are often invo...
The hippocampus is remarkably plastic and has the ability to modify its processes throughput the lif...
The interest for the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis and its role in the...
The interest for the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis and its role in the...
Contributions of somatotropic hormonal activity to memory functions in humans, which are suggested b...
Cognitive impairment is common after stroke, and disturbances in hippocampal function are often invo...
Cataloged from PDF version of article.Alterations in the alpha-amino-3-hydroxy-5-methyl-4-isoxazolep...