Synthetically-derived S,S-heterodisubstituted disulfides that exhibit potent in vitro antibacterial activity against a variety of bacteria, including Staphylococcus aureus, methicillin-resistant Staphylococcus aureus and Francisella tularensis. The present invention provides compounds, methods and compositions effective to treat microbial/bacterial infections, and, especially, infections arising from bacteria which have developed resistance to conventional antibiotics
Abstract Disulfides from Allium stipitatum, commonly known as Persian shallot, were previously repor...
In bacteria, disulfide bonds confer stability on many proteins exported to the cell envelope or beyo...
Abstract: A novel series of dihydropyrrol-2-one compounds bearing sulfonamide groups were synthesize...
Synthetically-derived S,S-heterodisubstituted disulfides that exhibit potent in vitro antibacterial ...
Antibiotic resistance is a particularly critical health concern and has increased dramatically over ...
The invention relates to heterosubstituted N-thiolated beta-lactams, compositions comprising these c...
The present invention provides N-alkylthio β-lactams and disulfide compounds (e.g., alkyl-coenzyme A...
Thio-Schiff bases are becoming increasingly widespread in various branches such as the preparation o...
Sixteen disulfides derived from disulfiram (Antabuse™) were evaluated as antibacterial agents. Deriv...
This study describes the antibacterial properties of synthetically-produced mixed aryl alkyl disulfi...
A chemical library comprised of nineteen synthesized pyridyl disulfides that emulate the chemical re...
The invention relates generally to novel N-thiolated β-lactams. More specially, the invention relate...
Abstract Disulfides from Allium stipitatum, commonly known as Persian shallot, were previously repor...
In bacteria, disulfide bonds confer stability on many proteins exported to the cell envelope or beyo...
Abstract: A novel series of dihydropyrrol-2-one compounds bearing sulfonamide groups were synthesize...
Synthetically-derived S,S-heterodisubstituted disulfides that exhibit potent in vitro antibacterial ...
Antibiotic resistance is a particularly critical health concern and has increased dramatically over ...
The invention relates to heterosubstituted N-thiolated beta-lactams, compositions comprising these c...
The present invention provides N-alkylthio β-lactams and disulfide compounds (e.g., alkyl-coenzyme A...
Thio-Schiff bases are becoming increasingly widespread in various branches such as the preparation o...
Sixteen disulfides derived from disulfiram (Antabuse™) were evaluated as antibacterial agents. Deriv...
This study describes the antibacterial properties of synthetically-produced mixed aryl alkyl disulfi...
A chemical library comprised of nineteen synthesized pyridyl disulfides that emulate the chemical re...
The invention relates generally to novel N-thiolated β-lactams. More specially, the invention relate...
Abstract Disulfides from Allium stipitatum, commonly known as Persian shallot, were previously repor...
In bacteria, disulfide bonds confer stability on many proteins exported to the cell envelope or beyo...
Abstract: A novel series of dihydropyrrol-2-one compounds bearing sulfonamide groups were synthesize...