This invention describes the discovery and synthesis of N-thiolated 2-oxazolidinones as a new class of anti bacterial agents. These compounds can be synthesized from 2-oxazolidinones by Ndeprotection and N-sulfenylation. These new substances were found to exhibit potent anti-bacterial activity, including bacteriostatic properties against Staphylococcus spp., including methicillin resistant Staphylcoccus aureus (MRSA), and Bacillus spp., including Bacillus anthracis
against experimental bacterial infections. novel oxazolidinone antimicrobial agents, In vivo activit...
In this study, a series of 3-(3-pyridyl)-oxazolidone-5-methyl ester derivatives was synthesized and ...
An interesting new approach was developed for the synthesis of Evans’ chiral auxiliaries with excell...
This invention describes the discovery and synthesis of N-thiolated 2-oxazolidinones as a new class ...
This invention describes the discovery and synthesis of N-thiolated 2-oxazolidinones as ...
This invention describes the discovery and synthesis of N-thiolated 2-oxazolidinones as a new class ...
Abstract: Several oxazolidinones, which are a new class of synthetic antibacterial agents, display b...
Staphylococcus aureus is one of the most common causes of nosocomial infections. The purpose of this...
Abstract: Staphylococcus aureus is one of the most common causes of nosocomial infections. The purpo...
Antibiotic resistance is a particularly critical health concern and has increased dramatically over ...
The development of resistance by the antibiotics in the Gram-positive pathogenic bacteria over the l...
Novel antibacterial oxazolidinones bearing pyrrolidinone ring system at the C-5 side chain were synt...
Two oxazolidine-2-thiones, thio-analogs of linezolid, were synthesized and their antibacterial prope...
The oxazolidinones are a new chemical class of synthetic antimicrobials characterized by a unique me...
Oxazolidinones are a novel class of synthetic antibacterial agents that inhibit bacterial protein sy...
against experimental bacterial infections. novel oxazolidinone antimicrobial agents, In vivo activit...
In this study, a series of 3-(3-pyridyl)-oxazolidone-5-methyl ester derivatives was synthesized and ...
An interesting new approach was developed for the synthesis of Evans’ chiral auxiliaries with excell...
This invention describes the discovery and synthesis of N-thiolated 2-oxazolidinones as a new class ...
This invention describes the discovery and synthesis of N-thiolated 2-oxazolidinones as ...
This invention describes the discovery and synthesis of N-thiolated 2-oxazolidinones as a new class ...
Abstract: Several oxazolidinones, which are a new class of synthetic antibacterial agents, display b...
Staphylococcus aureus is one of the most common causes of nosocomial infections. The purpose of this...
Abstract: Staphylococcus aureus is one of the most common causes of nosocomial infections. The purpo...
Antibiotic resistance is a particularly critical health concern and has increased dramatically over ...
The development of resistance by the antibiotics in the Gram-positive pathogenic bacteria over the l...
Novel antibacterial oxazolidinones bearing pyrrolidinone ring system at the C-5 side chain were synt...
Two oxazolidine-2-thiones, thio-analogs of linezolid, were synthesized and their antibacterial prope...
The oxazolidinones are a new chemical class of synthetic antimicrobials characterized by a unique me...
Oxazolidinones are a novel class of synthetic antibacterial agents that inhibit bacterial protein sy...
against experimental bacterial infections. novel oxazolidinone antimicrobial agents, In vivo activit...
In this study, a series of 3-(3-pyridyl)-oxazolidone-5-methyl ester derivatives was synthesized and ...
An interesting new approach was developed for the synthesis of Evans’ chiral auxiliaries with excell...