International audienceClostridium difficile is an anaerobic and spore-forming bacterium responsible for 15-25% of postantibiotic diarrhea and 95% of pseudomembranous colitis. Peptidoglycan is a crucial element of the bacterial cell wall that is exposed to the host, making it an important target for the innate immune system. The C. difficile peptidoglycan is largely N-deacetylated on its glucosamine (93% of muropeptides) through the activity of enzymes known as N-deacetylases, and this N-deacetylation modulates host-pathogen interactions, such as resistance to the bacteriolytic activity of lysozyme, virulence, and host innate immune responses. C. difficile genome analysis showed that 12 genes potentially encode N-deacetylases; however, which...
Abstract Clostridium difficile is a Gram-positive, obligate anaerobe and an opportunistic pathogen ...
ABSTRACT Clostridioides difficile is the most common cause of nosocomial antibiotic-associated diarr...
International audienceSynthesis of the major toxin proteins of the diarrheal pathogen, Clostridium d...
International audienceClostridium difficile is an anaerobic and spore-forming bacterium responsible ...
Clostridium difficile est une bactérie anaérobie sporulante responsable de 15 à 25% des diarrhées po...
The structure of the vegetative cell wall peptidoglycan of Clostridium difficile was determined by a...
Listeria monocytogenes is a human intracellular pathogen that is able to survive in the gastrointest...
Listeria monocytogenes is a human intracellular pathogen that is able to survive in the gastrointest...
Ph. D. ThesisClostridioides difficile is a Gram-positive enteric human pathogen capable of colonisin...
In the past decade, Clostridium difficile has emerged as an important gut pathogen. Symptoms of C. d...
In the past decade, Clostridium difficile has emerged as an important gut pathogen. Symptoms of C. d...
Clostridium difficile is a diarrheagenic pathogen associated with significant mortality and morbidit...
Clostridium difficile is a is a Gram potential human pathogen. It causing symptoms ranging from mild...
In the past decade, Clostridium difficile has emerged as an important gut pathogen. Symptoms of C. d...
ABSTRACT The signaling molecule cyclic diguanylate (c-di-GMP) mediates physiological adaptation to e...
Abstract Clostridium difficile is a Gram-positive, obligate anaerobe and an opportunistic pathogen ...
ABSTRACT Clostridioides difficile is the most common cause of nosocomial antibiotic-associated diarr...
International audienceSynthesis of the major toxin proteins of the diarrheal pathogen, Clostridium d...
International audienceClostridium difficile is an anaerobic and spore-forming bacterium responsible ...
Clostridium difficile est une bactérie anaérobie sporulante responsable de 15 à 25% des diarrhées po...
The structure of the vegetative cell wall peptidoglycan of Clostridium difficile was determined by a...
Listeria monocytogenes is a human intracellular pathogen that is able to survive in the gastrointest...
Listeria monocytogenes is a human intracellular pathogen that is able to survive in the gastrointest...
Ph. D. ThesisClostridioides difficile is a Gram-positive enteric human pathogen capable of colonisin...
In the past decade, Clostridium difficile has emerged as an important gut pathogen. Symptoms of C. d...
In the past decade, Clostridium difficile has emerged as an important gut pathogen. Symptoms of C. d...
Clostridium difficile is a diarrheagenic pathogen associated with significant mortality and morbidit...
Clostridium difficile is a is a Gram potential human pathogen. It causing symptoms ranging from mild...
In the past decade, Clostridium difficile has emerged as an important gut pathogen. Symptoms of C. d...
ABSTRACT The signaling molecule cyclic diguanylate (c-di-GMP) mediates physiological adaptation to e...
Abstract Clostridium difficile is a Gram-positive, obligate anaerobe and an opportunistic pathogen ...
ABSTRACT Clostridioides difficile is the most common cause of nosocomial antibiotic-associated diarr...
International audienceSynthesis of the major toxin proteins of the diarrheal pathogen, Clostridium d...