Effect of dietary supplementation of essential oil of Pistacia atlantica on liver tissue, some blood parameters and performance of Oncorhynchus mykiss

Some herbs have a wide range of beneficial properties, including stimulating and strengthening the immune system, their use in fish farms improves growth. Sixty healthy rainbow trout were selected with 150 g weight. They were randomly divided into 2 groups of 30 each with 3 replications. The essential oil was added to the daily diet with 10 g / kg feed and after 3 months the fish were assayed and sampled. some blood parameters was performed. The results showed that the control group had lower food conversion ratio (p < 0.05). Also, consumption of essential oil at this dose had negative effect on liver function and liver enzymes significantly increased (p < 0.05). Total protein, albumin, and blood glucose were decreased and uric acid and creatinine were significantly increased (p < 0.05). The blood cells were significantly decreased. In the histological examination around the central veins of liver was severe degeneration. Evaluation of blood biochemical values showed that AST, ALT in the treatment group significantly increased and total protein and albumin in the treatment group decreased significantly (P <0.05). Uric acid was significantly higher in the treated fish than in the control group (P