Probing the polarity of spontaneous perisomatic GABAergic synaptic transmission in the mouse CA3 circuit in vivo
- Dubanet, Olivier
- Ferreira Gomes Da Silva, Arnaldo
- Frick, Andreas
- Hirase, Hajime
- Beyeler, Anna
- Leinekugel, Xavier
DOIAbstract
International audienceProbing the polarity of spontaneous perisomatic GABAergic synaptic transmission in the mouse CA3 circuit in vivo Graphical abstract Highlights d CA3 PV-interneurons generate perisomatic unitary GABAergic field potentials in vivo d GABAergic unitary fields can be used to probe inhibition with single-cell resolution d GABA reversal after acute seizures is restricted to the postictal silent period d GABAergic excitation during KA epileptogenesis is restricted to 0.6% of CA3 neuron
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