Association between postnatal growth and neurodevelopmental impairment by sex at 2 years of corrected age in a multi-national cohort of very preterm children
- El Rafei, Rym
- Jarreau, Pierre Henri
- Norman, Mikael
- Maier, Rolf Felix
- Barros, Henrique
- van Reempts, Patrick
- Pedersen, Pernille
- Cuttini, Marina
- Costa, Raquel
- Zemlin, Michael
- Draper, Elizabeth,
- Zeitlin, Jennifer
DOIAbstract
International audienceBackground & aims: Extra-uterine growth restriction (EUGR) is common among very preterm (VPT) infants and has been associated with impaired neurodevelopment. Some research suggests that adverse effects of EUGR may be more severe in boys. We investigated EUGR and neurodevelopment at 2 years of corrected age (CA) by sex in a VPT birth cohort.Methods: Data come from a population-based cohort of children born <32 weeks' gestation from 11 European countries and followed up at 2 years CA. Postnatal growth during the neonatal hospitalization was measured with: (1) birthweight and discharge-weight Z-score differences using Fenton charts (2) weight-gain velocity using Patel's model. Published cut-offs were used to define EUGR a...
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